| Adjunctive pharmacologic use in carotid endarterectomy: a review. | |
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MedLine Citation:
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PMID: 16956478 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Although carotid endarterectomy (CEA) is now widely accepted as the surgical therapy for carotid stenosis, the role of and indications and evidence for many pharmacologic agents that are used adjunctively in the perioperative setting have not been conclusively established. Aspirin (acetylsalicylic acid) is the pharmaceutical agent that has been studied most extensively in conjunction with CEA; other than aspirin and dextran, the use of many agents before, during, and after CEA has not been standardized. Prospective randomized trials are still needed to demonstrate efficacy, predict outcome, and determine the optimal use of these medications in their adjunctive use during CEA to improve patient care and obtain optimal surgical outcomes. |
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Authors:
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David Gortler; Stephen Maloney; Reuben Rutland; Tormod Westvik; Akihito Muto; Fabio A Kudo; Alan Dardik |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Vascular Volume: 14 ISSN: 1708-5381 ISO Abbreviation: Vascular Publication Date: 2006 Mar-Apr |
Date Detail:
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Created Date: 2006-09-07 Completed Date: 2007-05-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101196722 Medline TA: Vascular Country: Canada |
Other Details:
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Languages: eng Pagination: 93-102 Citation Subset: IM |
Affiliation:
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VA Connecticut Healthcare System, West Haven, CT, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic beta-Antagonists Anesthetics, Local Angiotensin-Converting Enzyme Inhibitors / therapeutic use Anti-Inflammatory Agents, Non-Steroidal / therapeutic use Anticoagulants / therapeutic use Aspirin / therapeutic use Carotid Stenosis / drug therapy, therapy* Chemotherapy, Adjuvant Endarterectomy, Carotid / methods* Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic beta-Antagonists; 0/Anesthetics, Local; 0/Angiotensin-Converting Enzyme Inhibitors; 0/Anti-Inflammatory Agents, Non-Steroidal; 0/Anticoagulants; 0/Hydroxymethylglutaryl-CoA Reductase Inhibitors; 50-78-2/Aspirin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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