Document Detail

Adiposity is not altered in preterm infants fed with a nutrient-enriched formula after hospital discharge.
MedLine Citation:
PMID:  20216105     Owner:  NLM     Status:  MEDLINE    
To determine whether adiposity was altered, body size (weight, length) and composition, determined by dual energy x-ray absorptiometry, were examined in preterm infants fed with a nutrient enriched (A, n=56), a term infant (B, n=57) or the nutrient enriched (discharge and term) plus the term formula (term and 6 mo; C, n=26), and a group of breast-fed preterm infants (D, n=25) at hospital discharge, 3, 6, and 12 mo corrected age. The results were analyzed using standard statistics. One hundred sixty-four infants (birth weight=1406+/-248 g, GA=31+/-1.7 wk) were studied. All infants underwent "catch-up," but weight and length were greater in infants in group A compared with groups B, C, or D. More rapid and complete "catch-up" was paralleled by increased total nonfat and fat mass (g) but not percentage of fat mass. Changes in fat mass (g) were primarily explained by increased fat accretion on the legs. More rapid and complete "catch-up" growth, therefore, reflected increased nonfat and peripheral fat mass. These data do not support the hypothesis of increased or central adiposity in infants fed a nutrient-enriched formula after hospital discharge.
Richard J Cooke; Ian J Griffin; Kenny McCormick
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pediatric research     Volume:  67     ISSN:  1530-0447     ISO Abbreviation:  Pediatr. Res.     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-05-18     Completed Date:  2010-08-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0100714     Medline TA:  Pediatr Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  660-4     Citation Subset:  IM    
Department of Pediatrics, Cardinal Glennon Children's Hospital, St Louis, Missouri 63104, USA.
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MeSH Terms
Absorptiometry, Photon
Age Factors
Birth Weight
Body Height
Breast Feeding*
Double-Blind Method
Head / anatomy & histology
Infant Formula*
Infant Nutritional Physiological Phenomena*
Infant, Newborn
Infant, Premature / growth & development*
Patient Discharge*
Prospective Studies
Weight Gain

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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