Document Detail

Adipose tissue fatty acids as biomarkers of dietary exposure in Danish men and women.
MedLine Citation:
PMID:  8480677     Owner:  NLM     Status:  MEDLINE    
Adipose tissue fatty acids, it has been proposed, reflect dietary intake. Using data from a validation study preceding a prospective study on diet, cancer, and health in Denmark, we were able to compare fatty acid profiles in adipose tissue biopsies from 86 individuals (23 men and 63 women) aged 40-64 y and dietary intake of fatty acids (as percentage of total fat) assessed by two 7-d weighed-diet records or by a semi-quantitative food frequency questionnaire. Correlation coefficients (Pearson r) between fatty acid concentrations in adipose tissue biopsies (as percentage of total peak area) and dietary intake of fatty acid (percentage of total fat), determined from the diet records for men and women, respectively, were as follows: polyunsaturated fatty acids r = 0.74 and r = 0.46; n - 3 fatty acids of marine origin: eicosapentaenoic acid r = 0.15 and r = 0.61, and docosahexaenoic acid r = 0.47 and r = 0.57. Correlation coefficients obtained by using the food frequency questionnaire were slightly lower for most fatty acids.
A Tjønneland; K Overvad; E Thorling; M Ewertz
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of clinical nutrition     Volume:  57     ISSN:  0002-9165     ISO Abbreviation:  Am. J. Clin. Nutr.     Publication Date:  1993 May 
Date Detail:
Created Date:  1993-05-27     Completed Date:  1993-05-27     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376027     Medline TA:  Am J Clin Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  629-33     Citation Subset:  AIM; IM    
Danish Cancer Registry, Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen.
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MeSH Terms
Adipose Tissue / metabolism*
Biological Markers / analysis*
Denmark / epidemiology
Diet / statistics & numerical data
Dietary Fats / administration & dosage*
Fatty Acids / analysis*
Middle Aged
Nutrition Surveys
Reg. No./Substance:
0/Biological Markers; 0/Dietary Fats; 0/Fatty Acids

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