| Adiponectin responses to continuous and progressively intense intermittent exercise. | |
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MedLine Citation:
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PMID: 12900685 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: Adiponectin is a recently discovered adipocyte protein that is lower in patients with coronary artery disease and in Type II diabetics who have insulin resistance. Regular exercise is known to be a preventative factor in the development of atherosclerosis and Type II diabetes. Acute exercise increases insulin sensitivity; however, it also increases beta-adrenergic and glucocorticoid activities that may suppress adiponectin expression. Two experiments were conducted to determine whether acute exercise affects adiponectin concentrations. METHODS: In the first experiment, six healthy male subjects completed 30 min of heavy continuous running exercise at 79% of VO (2max). In the second experiment, well-trained runners completed strenuous intermittent exercise consisting of treadmill running at 60, 75, 90, and 100% VO (2max). A resting control trial for the second experiment was also conducted. RESULTS: Glucose and insulin were not altered significantly in the first experiment, but both increased significantly (P < 0.05) in the second experiment. A significant increase (P < 0.05) in adiponectin in the first experiment was no longer significant after correction for plasma volumes shifts. In the second experiment, there were significant (P < 0.05) changes in adiponectin concentrations over time but not a significant difference between adiponectin responses in exercise and control trials. CONCLUSIONS: The data suggest that 30 min of heavy continuous running or more strenuous intermittent running does not stimulate an increase in production and release of adiponectin, and small increases in adiponectin concentrations resulting from the exercise may be attributed to normal plasma volume shifts. |
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Authors:
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Robert R Kraemer; Karam S Aboudehen; Ann K Carruth; Robert T J Durand; Edmund O Acevedo; Edward P Hebert; Lisa G Johnson; V Daniel Castracane |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Medicine and science in sports and exercise Volume: 35 ISSN: 0195-9131 ISO Abbreviation: Med Sci Sports Exerc Publication Date: 2003 Aug |
Date Detail:
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Created Date: 2003-08-05 Completed Date: 2003-12-11 Revised Date: 2010-03-23 |
Medline Journal Info:
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Nlm Unique ID: 8005433 Medline TA: Med Sci Sports Exerc Country: United States |
Other Details:
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Languages: eng Pagination: 1320-5 Citation Subset: IM; S |
Affiliation:
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Department of Kinesiology and Health Studies, Southeastern Louisiana University, Hammond, LA 70402, USA. rkraemer@selu.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adiponectin Adult Blood Glucose / metabolism Exercise / physiology* Humans Insulin / blood Intercellular Signaling Peptides and Proteins* Lactic Acid / blood Male Oxygen Consumption / physiology Physical Endurance / physiology* Plasma Volume / physiology Proteins / metabolism* Running / physiology Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Adiponectin; 0/Blood Glucose; 0/Intercellular Signaling Peptides and Proteins; 0/Proteins; 11061-68-0/Insulin; 50-21-5/Lactic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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