Document Detail

Adipokinetic hormones: cell and molecular biology.
MedLine Citation:
PMID:  1601107     Owner:  NLM     Status:  MEDLINE    
Adipokinetic hormones AKH I (pGlu-Leu-Asn-Phe-Thr-Pro-Asn-Trp-Gly-Thr-NH2) and AKH II (pGlu-Leu-Asn-Phe-Ser-Trp-Gly-Thr-NH2) are synthesized by neurosecretory cells (NSC) of the corpora cardiaca (CC) in the locust, Schistocerca gregaria. These NSC constitute a homogeneous 'peptide factory' as each cell synthesizes both AKH I and AKH II. This homogeneity makes the CC an excellent system in which to study aspects of neuropeptide biosynthesis. This report summarizes recent findings on AKH inactivation and metabolism, as well as on AKH prohormone processing and biosynthesis.
M O'Shea; R C Rayne
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Experientia     Volume:  48     ISSN:  0014-4754     ISO Abbreviation:  Experientia     Publication Date:  1992 May 
Date Detail:
Created Date:  1992-07-14     Completed Date:  1992-07-14     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0376547     Medline TA:  Experientia     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  430-8     Citation Subset:  IM    
Sussex Centre for Neuroscience, School of Biological Sciences, University of Sussex, Falmer, Brighton, United Kingdom.
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MeSH Terms
Amino Acid Sequence
Base Sequence
Grasshoppers / metabolism*
Insect Hormones / biosynthesis,  chemistry,  genetics,  metabolism*
Molecular Sequence Data
Protein Precursors / biosynthesis
RNA, Messenger / chemistry
Reg. No./Substance:
0/Insect Hormones; 0/Protein Precursors; 0/RNA, Messenger; 53027-55-7/adipokinetic hormone (locust)

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