Document Detail

Adipokines and insulin resistance during pregnancy.
MedLine Citation:
PMID:  18291552     Owner:  NLM     Status:  MEDLINE    
Normal pregnancy has been characterized as a "diabetogenic state". On the other hand, the adipose tissue is now considered an active organ, capable of secreting substances such as adipokines, which may play a role in the pathogenesis of insulin resistance. Resistin, leptin serum and placental levels increase as pregnancy progresses, which is in contrast to levels of adiponectin. These levels correlate with the state of reduced insulin sensitivity often developed in the latter stages of pregnancy. The objective of this article is to review recent advances in our understanding of adipokines and insulin resistance during pregnancy.
Ana Bertha Zavalza-Gómez; Roberto Anaya-Prado; Ana Rosa Rincón-Sánchez; José Miguel Mora-Martínez
Publication Detail:
Type:  Journal Article; Review     Date:  2008-03-04
Journal Detail:
Title:  Diabetes research and clinical practice     Volume:  80     ISSN:  1872-8227     ISO Abbreviation:  Diabetes Res. Clin. Pract.     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-03-28     Completed Date:  2008-06-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8508335     Medline TA:  Diabetes Res Clin Pract     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  8-15     Citation Subset:  IM    
Division of Research, Hospital of Obstetrics and Gynecology at Western Medical Center, Mexican Institute of Social Security, Jalisco, Mexico.
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MeSH Terms
Adipokines / metabolism*
Diabetes, Gestational / metabolism*
Insulin / metabolism*
Insulin Resistance*
Placenta / metabolism*
Reg. No./Substance:
0/Adipokines; 11061-68-0/Insulin

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