Document Detail


Adherence to an (n-3) fatty acid/fish intake pattern is inversely associated with metabolic syndrome among Puerto Rican adults in the Greater Boston area.
MedLine Citation:
PMID:  20702744     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Combinations of fatty acids may affect risk of metabolic syndrome. Puerto Ricans have a disproportionate number of chronic conditions compared with other Hispanic groups. We aimed to characterize fatty acid intake patterns of Puerto Rican adults aged 45-75 y and living in the Greater Boston area (n = 1207) and to examine associations between these patterns and metabolic syndrome. Dietary fatty acids, as a percentage of total fat, were entered into principle components analysis. Spearman correlation coefficients were used to examine associations between fatty acid intake patterns, nutrients, and food groups. Associations with metabolic syndrome were analyzed by using logistic regression and general linear models with quintiles of principal component scores. Four principal components (factors) emerged: factor 1, short- and medium-chain SFA/dairy; factor 2, (n-3) fatty acid/fish; factor 3, very long-chain (VLC) SFA and PUFA/oils; and factor 4, monounsaturated fatty acid/trans fat. The SFA/dairy factor was inversely associated with fasting serum glucose concentrations (P = 0.02) and the VLC SFA/oils factor was negatively related to waist circumference (P = 0.008). However, these associations were no longer significant after additional adjustment for BMI. The (n-3) fatty acid/fish factor was associated with a lower likelihood of metabolic syndrome (Q5 vs. Q1: odds ratio: 0.54, 95% CI: 0.34, 0.86). In summary, principal components analysis of fatty acid intakes revealed 4 dietary fatty acid patterns in this population. Identifying optimal combinations of fatty acids may be beneficial for understanding relationships with health outcomes given their diverse effects on metabolism.
Authors:
Sabrina E Noel; P K Newby; Jose M Ordovas; Katherine L Tucker
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2010-08-11
Journal Detail:
Title:  The Journal of nutrition     Volume:  140     ISSN:  1541-6100     ISO Abbreviation:  J. Nutr.     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-21     Completed Date:  2010-10-19     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  0404243     Medline TA:  J Nutr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1846-54     Citation Subset:  IM    
Affiliation:
USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA.
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MeSH Terms
Descriptor/Qualifier:
Aged
Animals
Blood Glucose / analysis
Body Mass Index
Boston / epidemiology
Diet
Dietary Fats, Unsaturated / administration & dosage*
Fasting
Fatty Acids, Omega-3 / administration & dosage*
Female
Fishes*
Humans
Logistic Models
Male
Metabolic Syndrome X / diagnosis,  epidemiology*,  ethnology
Middle Aged
Puerto Rico / ethnology
Grant Support
ID/Acronym/Agency:
P01-AG023394/AG/NIA NIH HHS
Chemical
Reg. No./Substance:
0/Blood Glucose; 0/Dietary Fats, Unsaturated; 0/Fatty Acids, Omega-3
Comments/Corrections

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