| Adherence to an (n-3) fatty acid/fish intake pattern is inversely associated with metabolic syndrome among Puerto Rican adults in the Greater Boston area. | |
| | |
MedLine Citation:
|
PMID: 20702744 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Combinations of fatty acids may affect risk of metabolic syndrome. Puerto Ricans have a disproportionate number of chronic conditions compared with other Hispanic groups. We aimed to characterize fatty acid intake patterns of Puerto Rican adults aged 45-75 y and living in the Greater Boston area (n = 1207) and to examine associations between these patterns and metabolic syndrome. Dietary fatty acids, as a percentage of total fat, were entered into principle components analysis. Spearman correlation coefficients were used to examine associations between fatty acid intake patterns, nutrients, and food groups. Associations with metabolic syndrome were analyzed by using logistic regression and general linear models with quintiles of principal component scores. Four principal components (factors) emerged: factor 1, short- and medium-chain SFA/dairy; factor 2, (n-3) fatty acid/fish; factor 3, very long-chain (VLC) SFA and PUFA/oils; and factor 4, monounsaturated fatty acid/trans fat. The SFA/dairy factor was inversely associated with fasting serum glucose concentrations (P = 0.02) and the VLC SFA/oils factor was negatively related to waist circumference (P = 0.008). However, these associations were no longer significant after additional adjustment for BMI. The (n-3) fatty acid/fish factor was associated with a lower likelihood of metabolic syndrome (Q5 vs. Q1: odds ratio: 0.54, 95% CI: 0.34, 0.86). In summary, principal components analysis of fatty acid intakes revealed 4 dietary fatty acid patterns in this population. Identifying optimal combinations of fatty acids may be beneficial for understanding relationships with health outcomes given their diverse effects on metabolism. |
| | |
Authors:
|
Sabrina E Noel; P K Newby; Jose M Ordovas; Katherine L Tucker |
Related Documents
:
|
8123654 - Plasma essential fatty acids, cigarette smoking, and dietary antioxidants in peripheral... 3669924 - Interaction of (n-3) and (n-6) fatty acids in desaturation and chain elongation of esse... 8925184 - Polyunsaturated fatty acids and function of platelets and endothelial cells. 11895154 - Fatty acids and lymphocyte functions. 2329574 - Synthesis and antimalarial activity of (+)-deoxoartemisinin. 53074 - Reversed transport of amino acids in ehrlich cells. |
Publication Detail:
|
Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. Date: 2010-08-11 |
Journal Detail:
|
Title: The Journal of nutrition Volume: 140 ISSN: 1541-6100 ISO Abbreviation: J. Nutr. Publication Date: 2010 Oct |
Date Detail:
|
Created Date: 2010-09-21 Completed Date: 2010-10-19 Revised Date: 2012-05-07 |
Medline Journal Info:
|
Nlm Unique ID: 0404243 Medline TA: J Nutr Country: United States |
Other Details:
|
Languages: eng Pagination: 1846-54 Citation Subset: IM |
Affiliation:
|
USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Animals Blood Glucose / analysis Body Mass Index Boston / epidemiology Diet Dietary Fats, Unsaturated / administration & dosage* Fasting Fatty Acids, Omega-3 / administration & dosage* Female Fishes* Humans Logistic Models Male Metabolic Syndrome X / diagnosis, epidemiology*, ethnology Middle Aged Puerto Rico / ethnology |
| Grant Support | |
ID/Acronym/Agency:
|
P01-AG023394/AG/NIA NIH HHS |
| Chemical | |
Reg. No./Substance:
|
0/Blood Glucose; 0/Dietary Fats, Unsaturated; 0/Fatty Acids, Omega-3 |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Neuromodulation by GABA converts a relay into a coincidence detector.
Next Document: Long-Term Intermittent Multiple Micronutrient Supplementation Enhances Hemoglobin and Micronutrient ...