Document Detail

Adenosquamous carcinoma of the prostate.
MedLine Citation:
PMID:  10408308     Owner:  NLM     Status:  MEDLINE    
We present an unusual variant of prostatic adenocarcinoma with obvious squamous differentiation. The squamous component is represented by cells that contain vesicular or hyperchromatic nuclei and large acidophilic cytoplasm. We could demonstrate immunohistochemically the presence of prostate specific antigen (PSA) and glial fibrillary acidic protein (GFAP) in these tumour cells. Either in adenocarcinomatous or malignant squamous components, the prostatic epithelial cells showed the two markers, namely PSA, GFAP, which may reflect the multidirectional differentiation of these cells from a pluripotent origin.
O I Turhan; N E Aydin; O Sariyüce
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  International urology and nephrology     Volume:  31     ISSN:  0301-1623     ISO Abbreviation:  Int Urol Nephrol     Publication Date:  1999  
Date Detail:
Created Date:  1999-08-12     Completed Date:  1999-08-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0262521     Medline TA:  Int Urol Nephrol     Country:  HUNGARY    
Other Details:
Languages:  eng     Pagination:  89-93     Citation Subset:  IM    
Department of Pathology, Inönü University School of Medicine, Malatya, Turkey.
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MeSH Terms
Carcinoma, Adenosquamous / metabolism,  pathology*
Fatal Outcome
Middle Aged
Prostatic Neoplasms / metabolism,  pathology*

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