| Adenosine and verapamil-sensitive ventricular tachycardia originating from the left ventricle: radiofrequency catheter ablation. | |
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MedLine Citation:
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PMID: 1282244 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A ventricular tachycardia (VT) with right bundle branch block (RBBB) QRS morphology and left axis originating from the inferoapical segment of the left ventricle is described in a 49-year-old man without structural heart disease. This VT could be initiated during isoproterenol infusion and was terminated with intravenous administration of adenosine and verapamil. Radiofrequency ablation eliminated the tachycardia. Previous reports have suggested reentry as the mechanism for a verapamil-sensitive VT with this ECG morphology, while cAMP-mediated triggered activity has been proposed as a mechanism for VTs sensitive to adenosine. The latter more typically arise in the right ventricular outflow tract. The electrophysiological and electropharmacological characteristics of the tachycardia in this patient suggest that this VT morphology is not specific for a mechanism but rather for the location of the site of origin. |
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Authors:
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W A DeLacey; S Nath; D E Haines; M J Barber; J P DiMarco |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Pacing and clinical electrophysiology : PACE Volume: 15 ISSN: 0147-8389 ISO Abbreviation: Pacing Clin Electrophysiol Publication Date: 1992 Dec |
Date Detail:
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Created Date: 1993-02-02 Completed Date: 1993-02-02 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7803944 Medline TA: Pacing Clin Electrophysiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 2240-4 Citation Subset: IM |
Affiliation:
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Division of Cardiology, University of Virginia Health Sciences Center, Charlottesville 22908. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenosine
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pharmacology* Bundle-Branch Block / physiopathology Cardiac Pacing, Artificial Catheter Ablation* Electrocardiography Heart Conduction System / drug effects Humans Isoproterenol / diagnostic use Male Middle Aged Tachycardia, Ventricular / diagnosis, physiopathology, surgery* Ventricular Function, Left / physiology Verapamil / pharmacology* |
| Chemical | |
Reg. No./Substance:
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52-53-9/Verapamil; 58-61-7/Adenosine; 7683-59-2/Isoproterenol |
| Comments/Corrections | |
Comment In:
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Pacing Clin Electrophysiol. 1993 Sep;16(9):1906-7
[PMID:
7692426
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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