Document Detail

Adenosine stress thallium-201 myocardial perfusion imaging for detecting coronary artery disease at an early stage.
MedLine Citation:
PMID:  23694919     Owner:  NLM     Status:  In-Data-Review    
The aims of this study were to evaluate the diagnostic value of adenosine thallium-201 myocardial perfusion imaging and to compare it with exercise stress thallium-201 myocardial perfusion imaging for detecting coronary artery disease (CAD) at an early stage. Forty-one patients suspected with CAD were randomly divided into two groups. In Group 1 (n=21) adenosine stress was undertaken; the exercise stress myocardial perfusion imaging was performed in Group 2 (n=20). Coronary angiography (CAG) was performed in each patient within 2 weeks before or after single photon emission computed tomography (SPECT). Adenosine stress group vs. exercise stress group, the sensitivity was 92.86% vs. 100.0%, specificity 57.14% vs. 60.0%, positive predictive value 81.25% vs. 71.43%, negative predictive value 80.0% vs. 100.0%, accuracy 80.95% vs. 80.0% respectively. Detection rates of vessels of coronary artery lesions were 66.67% in Group 1 and 72.22% in Group 2 (P> 0.05). The side effects were mild and transient. Our results demonstrated that adenosine stress myocardial perfusion imaging is a safe and reliable diagnostic method for an early stage of CAD. As a comparative sensitivity and accuracy with exercise stress thallium-201 myocardial perfusion imaging, adenosine stress testing may provide a feasible alternative pharmacological stress method in myocardial SPECT for detection of CAD.
Gui-Bing Chen; Hua Wu; Xiao-Jiang He; Jin-Xiong Huang; Dan Yu; Wei-Yi Xu; Hao Yu
Related Documents :
23685299 - Impact of ad hoc percutaneous coronary intervention with drug-eluting stents in angina ...
7397969 - Qrs mapping in the evaluation of acute anterior myocardial infarction.
7471379 - Body surface detection of delayed depolarizations in patients with recurrent ventricula...
16640509 - Decision support for the initial triage of patients with acute coronary syndromes.
4013989 - Two-dimensional echocardiography versus surface electrocardiography for the diagnosis o...
24384289 - Single-vessel or multivessel pci in patients with multivessel disease presenting with n...
7780719 - Prevention of left ventricular thrombus formation during pneumatic pump assist.
8131439 - Doppler-derived aortic maximal acceleration. a reliable index of left ventricular systo...
11903359 - Association of a polymorphism of the ecnos gene with myocardial infarction in a subgrou...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of X-ray science and technology     Volume:  21     ISSN:  1095-9114     ISO Abbreviation:  J Xray Sci Technol     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-05-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9000080     Medline TA:  J Xray Sci Technol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  317-22     Citation Subset:  IM    
Department of Nuclear Medicine, The First Affiliated Hospital, Xiamen University, Xiamen, Fujian, China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Safety and efficacy of 120w high performance system greenlight laser vaporization for non-muscle-inv...
Next Document:  Blood Pressure Among Public Employees After the Great East Japan Earthquake: The Watari Study.