Document Detail

Adenosine can improve the intra-atrial conduction block along the mitral annulus during accessory pathway ablation.
MedLine Citation:
PMID:  18308752     Owner:  NLM     Status:  MEDLINE    
A 10-year-old boy with a supraventricular tachycardia was referred for catheter ablation. An electrophysiologic study revealed a left lateral concealed accessory pathway (AP). A few radiofrequency (RF) applications targeting the AP resulted in an inadvertent intra-atrial conduction block at the mitral isthmus without any damage to the AP. Adenosine was then administered during left ventricular pacing. Soon after that, the conduction at the mitral isthmus recovered partially, and that change disappeared soon. Those findings suggested that the administration of adenosine may transiently recover the conduction at the mitral isthmus damaged by RF ablation.
Takumi Yamada; Yung R Lau; H Thomas McElderry; Harish Doppalapudi; G Neal Kay
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology     Volume:  10     ISSN:  1532-2092     ISO Abbreviation:  Europace     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-02-29     Completed Date:  2008-06-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883649     Medline TA:  Europace     Country:  England    
Other Details:
Languages:  eng     Pagination:  303-5     Citation Subset:  IM    
Division of Cardiovascular Diseases, University of Alabama at Birmingham, VH B147, 1670 University Boulevard, 1530 3rd Avenue South, Birmingham, AL 35294-0019, USA.
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MeSH Terms
Accessory Nerve / surgery*
Adenosine / pharmacology*
Anti-Arrhythmia Agents / pharmacology*
Catheter Ablation / methods*
Heart Conduction System / drug effects*,  physiopathology
Mitral Valve / drug effects*,  physiopathology
Tachycardia, Supraventricular / surgery*
Treatment Outcome
Ventricular Dysfunction, Left / physiopathology
Reg. No./Substance:
0/Anti-Arrhythmia Agents; 58-61-7/Adenosine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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