Document Detail


Adenosine 3',5' cyclic monophosphate, calcium and magnesium excretion in ethanol intoxication and hangover.
MedLine Citation:
PMID:  232365     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Effect of ethanol on adenosine 3', 5' cyclic monophosphate (cAMP), calcium (Ca) and magnesium (Mg) excretion was studied in controlled clinical conditions in man. Seven male volunteers served as their own controls. In 5 subjects cAMP excretion was primarily suppressed by ethanol. Ethanol appeared to have a biphasic effect on Ca excretion, an initial stimulation followed by a conservation phase. Mg excretion was stimulated by ethanol in 5 subjects. Subjects having nausea and vomitus and the most severe hangover symptoms had the lowest urinary Ca excretion and the lowest imitial cAMP excretion. Ca and Mg metabolism and the susceptibility of the body to the toxic effects of ethanol appeared to be interrelated.
Authors:
J Linkola; F Fyhrquist; R Ylikahri
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta physiologica Scandinavica     Volume:  107     ISSN:  0001-6772     ISO Abbreviation:  Acta Physiol. Scand.     Publication Date:  1979 Dec 
Date Detail:
Created Date:  1980-06-25     Completed Date:  1980-06-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370362     Medline TA:  Acta Physiol Scand     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  333-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Alcoholic Intoxication / urine*
Calcium / urine*
Cyclic AMP / urine*
Ethanol / pharmacology*
Humans
Magnesium / urine*
Male
Chemical
Reg. No./Substance:
60-92-4/Cyclic AMP; 64-17-5/Ethanol; 7439-95-4/Magnesium; 7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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