Document Detail

Adenoma of the papilla and ampulla--premalignant lesions?
MedLine Citation:
PMID:  11382317     Owner:  NLM     Status:  MEDLINE    
Ampullary adenomas arising in the papilla or the ampulla Vateri, are rare, benign, neoplastic lesions. No specific aetiological factors, such as diet, chemical or environmental causes, have been identified yet. An established risk factor which is accompanied by the development of adenoma is the presence of genetically inherited polyposis syndromes, e.g. familial adenomatosis coli (FAP). Adenomas assume tubular, tubulovillous, or villous architecture and are not different from adenomas arising elsewhere in the gastrointestinal tract. The full neoplastic spectrum, ranging from mild to high grade dysplasia, up to invasive carcinoma, resembles the adenoma-carcinoma sequence of the large bowels.
C Wittekind; A Tannapfel
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Langenbeck's archives of surgery / Deutsche Gesellschaft für Chirurgie     Volume:  386     ISSN:  1435-2443     ISO Abbreviation:  Langenbecks Arch Surg     Publication Date:  2001 Apr 
Date Detail:
Created Date:  2001-05-30     Completed Date:  2001-10-11     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9808285     Medline TA:  Langenbecks Arch Surg     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  172-5     Citation Subset:  IM    
Institute of Pathology, University of Leipzig, Germany.
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MeSH Terms
Adenoma* / genetics,  pathology
Adenomatous Polyposis Coli / genetics
Ampulla of Vater*
Common Bile Duct Neoplasms* / pathology
Precancerous Conditions* / genetics,  pathology
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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