Document Detail


Adenoid cystic carcinoma of the trachea treated with PET-CT based intensity modulated radiotherapy.
MedLine Citation:
PMID:  18594327     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Primary tumors of the trachea are rare and are usually malignant in adults and benign in children. Adenoid cystic carcinoma, which is of salivary gland origin, account for about one thirds of adult primary tracheal tumors. A 49-year-old gentleman presented to us after undergoing a pneumonectomy elsewhere. Computed tomography scan of the thorax at our hospital showed a residual disease in the primary site, size of which was same as that in the preoperative scan. Because there was a compromised respiratory reserve due to pneumonectomy we decided to keep the radiation dose to the remaining lung as low as possible. We treated him by positron emission tomography-computed tomography (PET-CT) directed intensity modulated radiation therapy to a dose of 60 Gy in 30 Fractions over 6 weeks on a linear accelerator. PET helped in exact localization of the target on the planning CT. He tolerated the treatment very well. PET-CT done 1 year posttreatment showed no residual disease. Presently he is disease free with good pulmonary reserve.
Authors:
Kunhi Parambath Haresh; Ramachandran Prabhakar; Goura K Rath; Daya Nand Sharma; Pramod K Julka; V Subramani
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer     Volume:  3     ISSN:  1556-1380     ISO Abbreviation:  J Thorac Oncol     Publication Date:  2008 Jul 
Date Detail:
Created Date:  2008-07-02     Completed Date:  2008-08-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101274235     Medline TA:  J Thorac Oncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  793-5     Citation Subset:  IM    
Affiliation:
Department of Radiotherapy and Oncology, All India Institute of Medical Sciences, New Delhi, India. kpharesh@rediffmail.com
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MeSH Terms
Descriptor/Qualifier:
Carcinoma, Adenoid Cystic / radiography,  radionuclide imaging,  radiotherapy*
Fluorodeoxyglucose F18 / diagnostic use
Humans
Male
Middle Aged
Neoplasm, Residual / radiography,  radionuclide imaging,  radiotherapy
Positron-Emission Tomography*
Radiography, Interventional
Radiopharmaceuticals / diagnostic use
Radiotherapy, Intensity-Modulated*
Tomography, X-Ray Computed*
Tracheal Neoplasms / radiography,  radionuclide imaging,  radiotherapy*
Chemical
Reg. No./Substance:
0/Radiopharmaceuticals; 63503-12-8/Fluorodeoxyglucose F18

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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