| Adenocarcinoma of the third duodenal portion: Case report and review of literature. | |
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MedLine Citation:
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PMID: 22347539 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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We focus on the diagnostic and therapeutic problems of duodenal adenocarcinoma, reporting a case and reviewing the literature. A 65-year old man with adenocarcinoma in the third duodenal portion was successfully treated with a segmental resection of the third part of the duodenum, avoiding a duodeno-cephalo-pancreatectomy. This tumor is very rare and frequently affects the III and IV duodenal portion. A precocious diagnosis and the exact localization of this neoplasia are crucial factors in order to decide the surgical strategy. Given a non-specificity of symptoms, endoscopy with biopsy is the diagnostic gold standard. Duodeno-cephalo-pancreatectomy (DCP) and segmental resection of the duodenum (SRD) are the two surgical options, with overlapping morbidity (27% vs 18%) and post operative mortality (3% vs 1%). The average incidence of postoperative long-term survival is 100%, 73.3% and 31.6% of cases after 1, 3 and 5 years from surgery, respectively. Long-term survival is made worse by two factors: the presence of metastatic lymph nodes and tumor localization in the proximal duodenum. The two surgical options are radical: DCP should be used only for proximal localizations while SRD should be chosen for distal localizations. |
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Authors:
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Federico Sista; Giuseppe De Santis; Antonio Giuliani; Emanuela Marina Cecilia; Federica Piccione; Laura Lancione; Sergio Leardi; Gianfranco Amicucci |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: World journal of gastrointestinal surgery Volume: 4 ISSN: 1948-9366 ISO Abbreviation: World J Gastrointest Surg Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-02-20 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101532473 Medline TA: World J Gastrointest Surg Country: China |
Other Details:
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Languages: eng Pagination: 23-6 Citation Subset: - |
Affiliation:
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Federico Sista, Giuseppe De Santis, Antonio Giuliani, Emanuela Marina Cecilia, Federica Piccione, Laura Lancione, Sergio Leardi, Gianfranco Amicucci, General Surgery, Department of Surgery, University of L'Aquila, 67100 L'Aquila, Italy. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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