Document Detail

Adenocarcinoma of the third duodenal portion: Case report and review of literature.
MedLine Citation:
PMID:  22347539     Owner:  NLM     Status:  PubMed-not-MEDLINE    
We focus on the diagnostic and therapeutic problems of duodenal adenocarcinoma, reporting a case and reviewing the literature. A 65-year old man with adenocarcinoma in the third duodenal portion was successfully treated with a segmental resection of the third part of the duodenum, avoiding a duodeno-cephalo-pancreatectomy. This tumor is very rare and frequently affects the III and IV duodenal portion. A precocious diagnosis and the exact localization of this neoplasia are crucial factors in order to decide the surgical strategy. Given a non-specificity of symptoms, endoscopy with biopsy is the diagnostic gold standard. Duodeno-cephalo-pancreatectomy (DCP) and segmental resection of the duodenum (SRD) are the two surgical options, with overlapping morbidity (27% vs 18%) and post operative mortality (3% vs 1%). The average incidence of postoperative long-term survival is 100%, 73.3% and 31.6% of cases after 1, 3 and 5 years from surgery, respectively. Long-term survival is made worse by two factors: the presence of metastatic lymph nodes and tumor localization in the proximal duodenum. The two surgical options are radical: DCP should be used only for proximal localizations while SRD should be chosen for distal localizations.
Federico Sista; Giuseppe De Santis; Antonio Giuliani; Emanuela Marina Cecilia; Federica Piccione; Laura Lancione; Sergio Leardi; Gianfranco Amicucci
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  World journal of gastrointestinal surgery     Volume:  4     ISSN:  1948-9366     ISO Abbreviation:  World J Gastrointest Surg     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-02-20     Completed Date:  2012-10-02     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101532473     Medline TA:  World J Gastrointest Surg     Country:  China    
Other Details:
Languages:  eng     Pagination:  23-6     Citation Subset:  -    
Federico Sista, Giuseppe De Santis, Antonio Giuliani, Emanuela Marina Cecilia, Federica Piccione, Laura Lancione, Sergio Leardi, Gianfranco Amicucci, General Surgery, Department of Surgery, University of L'Aquila, 67100 L'Aquila, Italy.
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