Document Detail

Adenocarcinoma arising below an ileoanal anastomosis after restorative proctocolectomy for ulcerative colitis: report of a case.
MedLine Citation:
PMID:  17593481     Owner:  NLM     Status:  MEDLINE    
We report a case of adenocarcinoma developing in remnant rectal mucosa below a hand-sewn ileal pouch-anal anastomosis (IPAA) after restorative proctocolectomy for ulcerative colitis (UC). To our knowledge, this is the first such case to be reported from Japan. A 60-year-old man with a 13-year history of UC underwent proctocolectomy with a hand-sewn IPAA and mucosectomy for anal stenosis and serious tenesmic symptoms. About 7 years later, a follow-up endoscopy showed a flat elevated malignant lesion, 2 cm in diameter, below the ileoanal anastomosis. He was treated by abdominoperineal resection of the pouch and anus with total mesorectal excision. Histopathological examination of the resected specimen confirmed the presence of a well-differentiated adenocarcinoma but there were no metastatic lymph nodes. He recovered uneventfully and remains well without evidence of recurrent disease 2 years and 3 months after his last operation.
Hirofumi Ota; Keiji Yamazaki; Wakio Endoh; Shigeyuki Hojo; Hiroki Fukunaga; Setsuko Yoshioka; Yoshihiro Okada; Shigeru Okamoto; Nobuhisa Ueda; Yoshiichi Maeura
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2007-06-26
Journal Detail:
Title:  Surgery today     Volume:  37     ISSN:  0941-1291     ISO Abbreviation:  Surg. Today     Publication Date:  2007  
Date Detail:
Created Date:  2007-06-26     Completed Date:  2007-09-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204360     Medline TA:  Surg Today     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  596-9     Citation Subset:  IM    
Department of Surgery, Osaka Saiseikai Senri Hospital, 1-1 D6 Tsukumodai, Suita, Osaka, 565-0862, Japan.
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MeSH Terms
Adenocarcinoma, Mucinous / etiology*,  pathology
Anastomosis, Surgical / adverse effects
Anus Neoplasms / etiology*,  pathology
Colitis, Ulcerative / complications*,  surgery
Follow-Up Studies
Ileum / surgery*
Intestinal Mucosa
Middle Aged
Postoperative Complications
Proctocolectomy, Restorative / adverse effects*
Rectum / surgery*

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