| Adenocarcinoma of the rectum in a 13-year-old girl with Turner syndrome. | |
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MedLine Citation:
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PMID: 20818275 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We describe a 13-year-old girl with short stature and delayed puberty who presented with hematochezia and recurrent abdominal pain for 1 year, and progressive weight loss for 6 months. Per rectal examination was suggestive of a rectal mass. Histopathologic evaluation of the proctoscopy-guided biopsy specimen showed rectal adenocarcinoma. Computerized tomography of the abdomen showed hepatic metastases, which was confirmed by fine-needle aspiration cytology of the liver. She also had perirectal, aortocaval, para-aotic, mesenteric, and gastrohepatic ligament lymph node enlargement. GTG-banded chromosomal analysis showed a karyotype of 45, X, confirming Turner syndrome. A brief review of the neoplasms described in literature in association with Turner syndrome, and the possible pathogenetic mechanisms are discussed. |
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Authors:
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Sriram Krishnamurthy; Nilay Nirupam; Anju Seth; Anil K Agarwal; Praveen Kumar; Satinder Aneja |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of pediatric hematology/oncology Volume: 33 ISSN: 1536-3678 ISO Abbreviation: J. Pediatr. Hematol. Oncol. Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-04-25 Completed Date: 2011-06-30 Revised Date: 2011-10-06 |
Medline Journal Info:
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Nlm Unique ID: 9505928 Medline TA: J Pediatr Hematol Oncol Country: United States |
Other Details:
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Languages: eng Pagination: 320-2 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Lady Hardinge Medical College and associated Kalawati Saran Children's Hospital, New Delhi, India. drsriramk@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abdominal Pain
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etiology,
pathology,
radiography Adenocarcinoma / complications*, pathology, radiography Adolescent Biopsy Female Humans Rectal Neoplasms / complications*, pathology, radiography Tomography, X-Ray Computed Turner Syndrome / complications* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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