| Adenine nucleotide and phosphoenolpyruvate transport by bovine chromaffin granule "ghosts". | |
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MedLine Citation:
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PMID: 6621884 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Purified bovine adrenal chromaffin granule "ghosts" (resealed membranes) accumulate nucleotides and phosphoenolpyruvate in a temperature-dependent process. Equilibration takes several hours, the compounds being accumulated to not more than twice their concentration in the medium. This uptake occurs primarily by a non-saturable diffusion process, and rates and extents show little dependence on membrane energization. Uptake rates are inhibited less than 50% by compounds that discharge the "ghost" membrane potential, or by atractylate or low concentrations of Cibacron Blue. The data gave little support to the theory that chromaffin granules have a membrane potential-dependent adenine nucleotide transport process and that nucleotides are in equilibrium with the positive-inside potential across the granule membrane. |
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Authors:
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H A Grüninger; D K Apps; J H Phillips |
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Publication Detail:
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Type: Comparative Study; In Vitro; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Neuroscience Volume: 9 ISSN: 0306-4522 ISO Abbreviation: Neuroscience Publication Date: 1983 Aug |
Date Detail:
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Created Date: 1983-11-23 Completed Date: 1983-11-23 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7605074 Medline TA: Neuroscience Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 917-24 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenine Nucleotides
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metabolism* Adenosine Diphosphate / metabolism Adenosine Monophosphate / metabolism Adenosine Triphosphate / metabolism Adrenal Medulla / metabolism* Animals Biological Transport, Active Cattle Chromaffin Granules / metabolism* Chromaffin System / metabolism* Energy Metabolism Membrane Potentials Phosphoenolpyruvate / metabolism* |
| Chemical | |
Reg. No./Substance:
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0/Adenine Nucleotides; 56-65-5/Adenosine Triphosphate; 58-64-0/Adenosine Diphosphate; 61-19-8/Adenosine Monophosphate; 73-89-2/Phosphoenolpyruvate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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