Document Detail


Addressing vitamin D deficiency in Canada: a public health innovation whose time has come.
MedLine Citation:
PMID:  20413135     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
There is disturbing evidence of widespread vitamin D deficiency in many population groups, particularly within nations at high latitude. Numerous recent studies in the scientific literature associate vitamin D deficiency with a colossal increase in morbidity and mortality. Since Canada is at higher latitude, this review assesses the vitamin D status within the Canadian population. This review was prepared by assessing available medical and scientific literature from Medline, as well as by reviewing several books and conference proceedings. A standard 25(OH)D level of 75-80nmol/l or more was used to indicate vitamin D sufficiency. Between 70% and 97% of Canadians demonstrate vitamin D insufficiency. Furthermore, studies assessing 25(OH)D levels of vitamin D at 25-40nmol/l reveal that many Canadians have profoundly deficient levels. Repletion of vitamin D3 with 2000IU/day for those not receiving judicious sun exposure and those with no contra-indications would likely achieve normalized levels in more than 93% of patients, without risk of toxicity. Explicit directives regarding vitamin D assessment and management are urgently required.
Authors:
G K Schwalfenberg; S J Genuis; M N Hiltz
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Publication Detail:
Type:  Journal Article; Review     Date:  2010-04-21
Journal Detail:
Title:  Public health     Volume:  124     ISSN:  1476-5616     ISO Abbreviation:  Public Health     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-07-08     Completed Date:  2010-11-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376507     Medline TA:  Public Health     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  350-9     Citation Subset:  IM    
Copyright Information:
Copyright 2010 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.
Affiliation:
Faculty of Medicine, University of Alberta, 301, 9509-156 Street, Edmonton, Alberta T5P 4J5, Canada. schwalfe@ualberta.ca
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MeSH Terms
Descriptor/Qualifier:
Canada / epidemiology
Humans
Risk Factors
Vitamin D / immunology,  physiology,  therapeutic use
Vitamin D Deficiency / epidemiology*,  ethnology,  therapy*
Chemical
Reg. No./Substance:
1406-16-2/Vitamin D

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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