| Addressing and managing erectile dysfunction after prostatectomy for prostate cancer. | |
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MedLine Citation:
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PMID: 20648854 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Erectile dysfunction is the most common side effect after prostatectomy. There are currently five categories of available treatment options for erectile dysfunction for men following radical prostatectomy. The first and most common treatment is oral phosphodiesterase type 5 inhibitors (sildenafil, vardenafil, or tadalafil). Despite their popularity, these medications do not always produce an erection sufficient for intercourse after prostatectomy. The second treatment option is the noninvasive option of either a venous constriction band or the vacuum constriction device. Both treatments use a venous occlusive tension band or ring to maintain erection by retaining blood in the penis. The vacuum constriction device also utilizes external suction pressure to create an erection prior to application of the tension ring. The third treatment option is Muses, an intraurethral suppository containing alprostadil that dilates the penile blood vessels. The fourth treatment option involves penile injections. The fifth treatment is the penile prosthesis, in which artificial rods are surgically implanted into the corpora cavernosa to provide penile rigidity. Oral agents, the vacuum device, Muse, and injections have been used for penile rehabilitation to encourage spontaneous return of erectile function in men after radical prostatectomy with varied success. Untreated erectile dysfunction after radical prostatectomy has been associated with penile atrophy and further diminished erectile function. Therefore, it is critically important that clinicians provide comprehensive information about the positive and negative aspects of all treatment options and the penile rehabilitation potential of each. This will enable patients to make informed treatment choices about early intervention for erectile dysfunction. |
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Authors:
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Jeffrey A Albaugh |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Urologic nursing Volume: 30 ISSN: 1053-816X ISO Abbreviation: Urol Nurs Publication Date: 2010 May-Jun |
Date Detail:
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Created Date: 2010-07-22 Completed Date: 2010-08-18 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8812256 Medline TA: Urol Nurs Country: United States |
Other Details:
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Languages: eng Pagination: 167-177, 166 Citation Subset: N |
Affiliation:
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Jesse Brown VA Medical Center and Northwestern Memorial Center for Integrative Medicine and Wellness, Chicago, IL, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Alprostadil
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administration & dosage Erectile Dysfunction / drug therapy, etiology, therapy* Humans Male Penile Prosthesis Phosphodiesterase Inhibitors / administration & dosage Prostaglandins / administration & dosage Prostatectomy / adverse effects*, rehabilitation Prostatic Neoplasms / surgery* Vasodilator Agents / administration & dosage |
| Chemical | |
Reg. No./Substance:
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0/Phosphodiesterase Inhibitors; 0/Prostaglandins; 0/Vasodilator Agents; 745-65-3/Alprostadil |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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