Document Detail

Addressing the growing problem of multiple gestations created by assisted reproductive therapies.
MedLine Citation:
PMID:  16360495     Owner:  NLM     Status:  MEDLINE    
Iatrogenic multiple pregnancy is the most significant complication of assisted reproductive technology (ART). Approximately half of all children born subsequent to ART result from a plural gestation. Furthermore, the majority of triplets and higher order births are the product of ART. The risks for multiple pregnancy vary with practice patterns and the techniques used to achieve pregnancy. Recognizing the potential for serious morbidity associated with multiple pregnancies, infertility specialists have developed strategies to reduce the complication of multiple pregnancies while maintaining acceptable pregnancy rates. Implementation of these refined practices has led to a reduction in the incidence of higher order multiple births, although the incidence of twins has yet to be minimized. Further reduction in the incidence of multiple births after ART necessitates a redefinition of success to emphasize the healthy singleton birth rate, rather than crude pregnancy rates.
Gary S Nakhuda; Mark V Sauer
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Seminars in perinatology     Volume:  29     ISSN:  0146-0005     ISO Abbreviation:  Semin. Perinatol.     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-12-19     Completed Date:  2006-02-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7801132     Medline TA:  Semin Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  355-62     Citation Subset:  IM    
Division of Reproductive Endocrinology and Infertility, College of Physicians & Surgeons, Columbia University, New York, NY 10032, USA.
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MeSH Terms
Multiple Birth Offspring*
Pregnancy, Multiple*
Reproductive Techniques, Assisted / adverse effects*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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