| Additive effect of diets and training on total insulin-like growth factor-1 (IGF-1) in rats. | |
| | |
MedLine Citation:
|
PMID: 20347065 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVES: Although it is known that circulating levels of insulin-like growth factor-1 (IGF-1) are influenced by both physical exercise and dietary intake separately, there is little information regarding the additive effect of diets and training on IGF-1 regulation. To test this, we examined the combined effect of 30 days of two different diets (high-protein and high-carbohydrate) and exercise training on total IGF-1. MATERIALS AND METHODS: The study was carried out with four groups of rats; the sedentary group with standard diet (SS) (control group), standard diet with exercise (SE), high-protein diet with exercise (PE) and high-carbohydrate diet with exercise (CE). Serum IGF-1, insulin, corticosterone were analyzed. RESULTS: IGF-1 concentrations were decreased by exercise training (p<0.001) and only with protein diet (p<0.05). Physical training, with and without diet, decreased body weight and food intake (p<0.01) and increased corticosterone levels (p<0.05). Carbohydrate diet did not cause major hormonal and metabolic alterations. CONCLUSION: The main result of this study was the decreased levels of IGF-1 in spite of high-protein diet, which is known to enhance IGF-1 secretion, and the little changes with carbohydrate diet. This may be related to the negative energy balance as a result of the catabolic state induced by exercise training and decreased calorie intake in protein diet. Thus, it can be concluded that the caloric restriction, regardless of dietary composition, decreased IGF-1 secretion. |
| | |
Authors:
|
N El Elj; G Lac; B Alya; M Lasram; M Zaouali; Z Tabka; A Kammoun; N Gharbi; S El Fezaa |
Related Documents
:
|
8002125 - Dietary, serum and urine ascorbic acid status in male athletes. 7127655 - The response of serum lipids and lipoproteins to high intensity endurance training. 14985185 - Whole blood and mononuclear cell glutathione response to dietary whey protein supplemen... 7749425 - In-season dietary adequacy of trained male cross-country runners. 11352165 - Effects of brown midrib corn silage on the energy balance of dairy cattle. 1872395 - Effect of pluronic l81, a hydrophobic surfactant, on intestinal mucosal cholesterol hom... |
Publication Detail:
|
Type: Journal Article Date: 2010-03-26 |
Journal Detail:
|
Title: Annales d'endocrinologie Volume: 71 ISSN: 0003-4266 ISO Abbreviation: Ann. Endocrinol. (Paris) Publication Date: 2010 Sep |
Date Detail:
|
Created Date: 2010-08-30 Completed Date: 2010-12-23 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0116744 Medline TA: Ann Endocrinol (Paris) Country: France |
Other Details:
|
Languages: eng Pagination: 297-302 Citation Subset: IM |
Copyright Information:
|
Copyright 2010 Elsevier Masson SAS. All rights reserved. |
Affiliation:
|
Laboratoire de physiologie animale, département de biologie, faculté des sciences de Tunis, campus universitaire, 1060 Tunis, Tunisia. naziha elj@yahoo.fr |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Body Weight Corticosterone / blood Diet* Dietary Carbohydrates / administration & dosage* Dietary Proteins / administration & dosage* Energy Intake Insulin / blood Insulin-Like Growth Factor I / analysis, metabolism* Male Physical Conditioning, Animal* Rats Rats, Wistar Sedentary Lifestyle* Swimming |
| Chemical | |
Reg. No./Substance:
|
0/Dietary Carbohydrates; 0/Dietary Proteins; 0/insulin-like growth factor-1, rat; 11061-68-0/Insulin; 50-22-6/Corticosterone; 67763-96-6/Insulin-Like Growth Factor I |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Polyelectrolyte condensation in bulk, at surfaces, and under confinement.
Next Document: Ergonomics and occupational safety and health: An ILO perspective.