| Additional left atrial septal line does not improve outcome of patients undergoing ablation for long-standing persistent atrial fibrillation. | |
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MedLine Citation:
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PMID: 20458822 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: Additional septal linear ablation in patients undergoing ablation of long-standing persistent atrial fibrillation (AF) could be beneficial due to additional extensive atrial tissue ablation and incidental ablation of sites with complex fractionated electrograms. We assessed the long-term outcome of patients after ablation of long-standing persistent AF with an additional left atrial (LA) septal line. METHODS: Thirty-four patients were included.The patients were randomized into two groups and underwent pulmonary vein (PV) isolation with roof line, mitral isthmus line and coronary sinus ablation. In group I an additional LA septal line was created. RESULTS: AF converted into atrial tachycardia in 2 patients during septal ablation in group I. In group 2 AF terminated via atrial tachycardia in 3 patients (P = ns). During a mean follow-up of 620 +/- 119 days, 7 (41%) and 8 (47%) patients from group 1 and group 2 were free from recurrences (P = ns). Redo procedures were performed in 5 patients of group 1 and in 5 patients of group 2. For a follow-up of 349 +/- 273 days after the last ablation, Cox's F-test showed a trend of more recurrences in group 1 (P = 0.07). CONCLUSIONS: In patients with long-standing AF, an additional LA septal linear ablation is not associated with a significantly higher AF termination rate. A septal linear lesion might increase the risk of septal reentrant tachycardias, and is associated with a trend towards a worse outcome. |
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Authors:
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Evgeny Mikhaylov; Sergey Gureev; Tamas Szili-Torok; Dmitry Lebedev |
Publication Detail:
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Type: Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Acta cardiologica Volume: 65 ISSN: 0001-5385 ISO Abbreviation: Acta Cardiol Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-05-12 Completed Date: 2010-06-11 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370570 Medline TA: Acta Cardiol Country: Belgium |
Other Details:
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Languages: eng Pagination: 153-60 Citation Subset: IM |
Affiliation:
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Department of Electrophysiology and Cardiac Pacing, Almazov Federal Heart, Blood and Endocrinology Centre, Saint-Petersburg, Russian Federation. evgenymikhaylov@gmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Atrial Fibrillation / physiopathology, surgery* Catheter Ablation* / methods Chronic Disease Electrocardiography Female Follow-Up Studies Heart Atria / physiopathology, surgery* Heart Conduction System / physiopathology, surgery* Humans Male Middle Aged Pulmonary Veins / physiopathology, surgery* Recurrence / prevention & control Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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