| Adding Folate to the Contraceptive Pill: A new Concept for the Prevention of Neural Tube Defects. | |
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MedLine Citation:
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PMID: 22272814 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Abstract Although it is proven for a long time that folic acid supplementation in the periconceptional period can prevent neural tube defects effectively, all measures taken so far including food fortification and awareness campagnes so far had only limited success. Since more than 50% of the pregnant women in Europe get pregnant after they have used oral contraceptoves before, OCs are an ideal vehicle to increase not only hte awareness for periconceptional folate application, but they can also help to bridge the gap between the recognition of a pregnancy and closure of the neural tube which is before day 26. In order to reach a truly protective folate level at the critical time period during pregnancy, now OCs are available which contain metafolin. The availability of this innovative type of OC will significantly reduce the number of neural tube defects. |
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Authors:
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Wolfgang Holzgreve; Klaus Pietrzik; Berthold Koletzko; Christel Eckmann-Scholz |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-24 |
Journal Detail:
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Title: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians Volume: - ISSN: 1476-4954 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-25 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101136916 Medline TA: J Matern Fetal Neonatal Med Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Institute of Advanced Research, Berlin,Germany ( wolfgang@holzgreve.net ). |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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