Document Detail


Addictive illegal drugs: structural neuroimaging.
MedLine Citation:
PMID:  19875473     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Illegal addictive drugs can lead to functional or structural impairment of the central nervous system. This review provides an overview of the structural imaging findings on CT, MR imaging, and conventional angiography related to chronic and acute abuse of the most commonly abused illegal drugs, including cannabis, organic solvents, and amphetamines and opioids and their respective derivatives. Pathomechanisms include excitotoxicity, which may lead to an acute or subacute leukoencephalopathy, and vascular complications, including vasoconstriction, vasculitis, or hypertension, which may lead to intracranial hemorrhage or ischemia. Because clinical findings alone are often nonspecific, and afflicted patients are unlikely to admit to the substance abuse, the neuroradiologist may play an important role in establishing the diagnosis and, thereby, initiating treatment.
Authors:
S Geibprasert; M Gallucci; T Krings
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Publication Detail:
Type:  Journal Article; Review     Date:  2009-10-29
Journal Detail:
Title:  AJNR. American journal of neuroradiology     Volume:  31     ISSN:  1936-959X     ISO Abbreviation:  AJNR Am J Neuroradiol     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-05-17     Completed Date:  2010-09-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8003708     Medline TA:  AJNR Am J Neuroradiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  803-8     Citation Subset:  IM    
Affiliation:
Division of Neuroradiology, Department of Diagnostic Radiology, University of Toronto, Hospital for Sick Children, Toronto, Ontario, Canada.
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MeSH Terms
Descriptor/Qualifier:
Brain Diseases / diagnosis*,  etiology
Cerebral Angiography / methods*
Humans
Magnetic Resonance Imaging / methods*
Street Drugs / poisoning*
Substance-Related Disorders / complications,  diagnosis*
Tomography, X-Ray Computed / methods*
Chemical
Reg. No./Substance:
0/Street Drugs

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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