| Added value of high-resolution MR imaging in the diagnosis of vertebral artery dissection. | |
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MedLine Citation:
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PMID: 20595374 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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MATERIALS AND METHODS: We retrospectively extracted 35 consecutive patients suspected of having acute VAD who had the following: 1) a focal lumen abnormality of the VA on CE-MRA, 2) HR-MR imaging during the initial hospital stay, and 3) clinical and imaging follow-up within 6 months. Two neurologists classified patients as either VAD (group A) or non-VAD (group B) by reviewing all the available data at hospital discharge, except HR-MR imaging data. On HR-MR imaging, 2 radiologists searched for signs of acute VAD. The 2 classifications were compared. In case of discordance, CE-MRA follow-up and axial fat-suppressed T1WI, used to obtain supportive evidence for or against VAD, were considered as the standard of reference. RESULTS: In 4/18 patients in group A, HR-MR imaging did not demonstrate any signs of acute VAD and perivertebral signal-intensity changes were attributed to venous plexus, with an unchanged lumen on follow-up. In 4/17 patients in group B, HR-MRI demonstrated a mural hematoma, with lumen normalization on follow-up CE-MRA. CONCLUSIONS: Our results encourage the use of HR-MR imaging as a second-line diagnostic tool in the event of suspicion of acute VAD and doubtful findings on standard imaging. |
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Authors:
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O Naggara; F Louillet; E Touzé; D Roy; X Leclerc; J-L Mas; J-P Pruvo; J-F Meder; C Oppenheim |
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Publication Detail:
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Type: Journal Article Date: 2010-07-01 |
Journal Detail:
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Title: AJNR. American journal of neuroradiology Volume: 31 ISSN: 1936-959X ISO Abbreviation: AJNR Am J Neuroradiol Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-10-11 Completed Date: 2011-02-22 Revised Date: 2011-06-30 |
Medline Journal Info:
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Nlm Unique ID: 8003708 Medline TA: AJNR Am J Neuroradiol Country: United States |
Other Details:
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Languages: eng Pagination: 1707-12 Citation Subset: IM |
Affiliation:
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Department of Neuroradiology, Paris-Descartes University, Centre Hospitalier Sainte-Anne, 1 rue Cabanis, Paris, France. o.naggara@ch-sainte-anne.fr |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Algorithms* Contrast Media Female Humans Image Enhancement / methods* Magnetic Resonance Angiography / methods* Male Meglumine / diagnostic use* Middle Aged Organometallic Compounds / diagnostic use* Reproducibility of Results Sensitivity and Specificity Vertebral Artery Dissection / pathology* |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/Organometallic Compounds; 0/gadoterate meglumine; 6284-40-8/Meglumine |
| Comments/Corrections | |
Comment In:
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AJNR Am J Neuroradiol. 2011 May;32(5):E91; author reply E92
[PMID:
21474631
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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