Document Detail

Adaptation of the vestibulo-ocular reflex, subjective tilt, and motion sickness to head movements during short-radius centrifugation.
MedLine Citation:
PMID:  14757910     Owner:  NLM     Status:  MEDLINE    
Head movements made while the whole body is rotating at unusually high angular velocities (here with supine body position about an earth-vertical axis) result in inappropriate eye movements, sensory illusions, disorientation, and frequently motion sickness. We investigated the acquisition and retention of sensory adaptation to cross-coupled components of the vestibulo-ocular reflex (VOR) by asking eight subjects to make headturns while being rotated at 23 rpm on two consecutive days, and again a week later. The dependent measures were inappropriate vertical VOR, subjective tilt, and motion sickness in response to 90 degrees yaw out-of-plane head movements. Motion sickness was evaluated during and following exposure to rotation. Significant adaptation effects were found for the slow phase velocity of vertical nystagmus, the reported magnitude of the subjective tilt experienced during head turns, and motion-sickness scores. Retention of adaptation over a six-day rest period without rotation occurred, but was not complete for all measures. Adaptation of VOR was fully maintained while subjective tilt was only partially maintained and motion-sickness scores continued to decrease. Practical implications of these findings are discussed with particular emphasis on artificial gravity, which could be produced in weightlessness by means of a short-radius (2 m) rotator.
Laurence R Young; Kathleen H Sienko; Lisette E Lyne; Heiko Hecht; Alan Natapoff
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Journal of vestibular research : equilibrium & orientation     Volume:  13     ISSN:  0957-4271     ISO Abbreviation:  J Vestib Res     Publication Date:  2003  
Date Detail:
Created Date:  2004-02-03     Completed Date:  2004-08-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9104163     Medline TA:  J Vestib Res     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  65-77     Citation Subset:  IM; S    
Man-Vehicle Lab Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
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MeSH Terms
Adaptation, Physiological*
Centrifugation / methods
Eye Movements
Head Movements
Motion Sickness / etiology*
Reflex, Vestibulo-Ocular / physiology*

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