Document Detail


Adaptation to stimulus statistics in the perception and neural representation of auditory space.
MedLine Citation:
PMID:  20620878     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Sensory systems are known to adapt their coding strategies to the statistics of their environment, but little is still known about the perceptual implications of such adjustments. We investigated how auditory spatial processing adapts to stimulus statistics by presenting human listeners and anesthetized ferrets with noise sequences in which interaural level differences (ILD) rapidly fluctuated according to a Gaussian distribution. The mean of the distribution biased the perceived laterality of a subsequent stimulus, whereas the distribution's variance changed the listeners' spatial sensitivity. The responses of neurons in the inferior colliculus changed in line with these perceptual phenomena. Their ILD preference adjusted to match the stimulus distribution mean, resulting in large shifts in rate-ILD functions, while their gain adapted to the stimulus variance, producing pronounced changes in neural sensitivity. Our findings suggest that processing of auditory space is geared toward emphasizing relative spatial differences rather than the accurate representation of absolute position.
Authors:
Johannes C Dahmen; Peter Keating; Fernando R Nodal; Andreas L Schulz; Andrew J King
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Neuron     Volume:  66     ISSN:  1097-4199     ISO Abbreviation:  Neuron     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-07-12     Completed Date:  2010-08-06     Revised Date:  2010-10-14    
Medline Journal Info:
Nlm Unique ID:  8809320     Medline TA:  Neuron     Country:  United States    
Other Details:
Languages:  eng     Pagination:  937-48     Citation Subset:  IM    
Affiliation:
Department of Physiology, Anatomy and Genetics, Sherrington Building, University of Oxford, Parks Road, Oxford OX1 3PT, UK. johannes.dahmen@dpag.ox.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Acoustic Stimulation / methods
Action Potentials / physiology
Adaptation, Physiological / physiology*
Analysis of Variance
Animals
Auditory Cortex / cytology
Auditory Perception / physiology*
Female
Ferrets
Humans
Linear Models
Male
Models, Neurological
Neurons / physiology*
Nonlinear Dynamics
Psychometrics
Psychophysics
Reaction Time
Space Perception / physiology*
Time Factors
Grant Support
ID/Acronym/Agency:
WT076508AIA//Wellcome Trust

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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