| Adaptation of intercalated cells along the collecting duct to systemic acid/base changes. | |
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MedLine Citation:
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PMID: 21030969 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Collecting duct intercalated cells respond to short-term acid/base perturbations by rapidly shuttling H(+)-ATPase to and from the plasma membrane. Purkerson et al. provide information on the regulation of the anion transporters during chronic acidosis and acute recovery (alkalosis). They found that the major mechanism for both acute and chronic states is regulation of both the H(+)-ATPase and the anion exchangers plus changes in the overall expression level of these anion transporters in chronic adaptation. |
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Authors:
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John H Schwartz; Edward A Alexander |
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Publication Detail:
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Type: Comment; Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
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Title: Kidney international Volume: 78 ISSN: 1523-1755 ISO Abbreviation: Kidney Int. Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-10-29 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0323470 Medline TA: Kidney Int Country: United States |
Other Details:
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Languages: eng Pagination: 949-51 Citation Subset: IM |
Affiliation:
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Renal Section, Boston University Medical Center and Boston University School of Medicine, Boston, Massachusetts, USA. jhsch@bu.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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| Grant Support | |
ID/Acronym/Agency:
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DK59529/DK/NIDDK NIH HHS |
| Comments/Corrections | |
Comment On:
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Kidney Int. 2010 Nov;78(10):993-1005
[PMID:
20592712
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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