| Adapalene gel 0.1% in the treatment of infantile acne: an open clinical study. | |
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MedLine Citation:
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PMID: 18577052 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Infantile acne is an uncommon condition in pediatric age. We determined the efficacy and safety of adapalene gel 0.1% in the treatment of infantile acne. Twelve patients were enrolled for adapalene gel 0.1% application once daily over a 16-week treatment period. Efficacy evaluation included counting the inflammatory and noninflammatory lesions by the physician and global evaluation of the improvement. After 16 weeks all patients were followed up for a 1-year period. The time of clearance of the infantile acne lesions was 3 months in four (33%) patients and 4 months in eight (67%) patients (median 3.4 months). Adapalene gel produced reductions in noninflammatory and inflammatory lesions counts. Limited side effects were observed and none of them required stopping the therapy. No patient was left with scarring. Three patients were showed mild lesions in the 1-year follow-up period. Adapalene gel 0.1% was found to be a highly effective and safe drug in the treatment of mild-to-moderate infantile acne. |
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Authors:
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Osman Kose; Erol Koç; Ercan Arca |
Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: Pediatric dermatology Volume: 25 ISSN: 1525-1470 ISO Abbreviation: Pediatr Dermatol Publication Date: 2008 May-Jun |
Date Detail:
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Created Date: 2008-06-25 Completed Date: 2008-08-28 Revised Date: 2013-05-24 |
Medline Journal Info:
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Nlm Unique ID: 8406799 Medline TA: Pediatr Dermatol Country: United States |
Other Details:
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Languages: eng Pagination: 383-6 Citation Subset: IM |
Affiliation:
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Department of Dermatology, Gülhane Military Medical Academy, School of Medicine Etlik, Ankara, Turkey. okose@gata.edu.tr |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acne Vulgaris
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drug therapy*,
pathology Administration, Cutaneous Analysis of Variance Child, Preschool Dermatologic Agents / adverse effects, therapeutic use* Erythema / chemically induced Face / pathology Female Gels Humans Infant Male Naphthalenes / adverse effects, therapeutic use* Pain / chemically induced Pruritus / chemically induced Skin / pathology Statistics, Nonparametric Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Dermatologic Agents; 0/Gels; 0/Naphthalenes; 1L4806J2QF/adapalene |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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