Acyclovir-induced neutropenia in an infant with herpes simplex encephalitis: case report. | |
MedLine Citation:
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PMID: 7548511 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A newborn infant whose condition was diagnosed as herpes simplex encephalitis and who had subsequent recurrences of skin disease had repeated episodes of neutropenia while receiving therapy with intravenous (30 mg/[kg.d]) or oral (30 mg/]kg.d]) acyclovir. The neutropenia did not recur when the dosage of oral acyclovir was reduced to 10 mg/(kg.d). This case represents the first well-documented report of acyclovir-induced neutropenia. |
Authors:
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H M Feder; R K Goyal; P J Krause |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Volume: 20 ISSN: 1058-4838 ISO Abbreviation: Clin. Infect. Dis. Publication Date: 1995 Jun |
Date Detail:
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Created Date: 1995-11-07 Completed Date: 1995-11-07 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9203213 Medline TA: Clin Infect Dis Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1557-9 Citation Subset: IM |
Affiliation:
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Department of Pediatrics and Family Medicine, University of Connecticut Health Center, Farmington 06030-3960, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
MeSH Terms | |
Descriptor/Qualifier:
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Acyclovir
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adverse effects*,
therapeutic use Encephalitis, Viral / cerebrospinal fluid, complications, drug therapy*, virology Female Follow-Up Studies Herpesvirus 2, Human* / drug effects Humans Infant, Newborn Magnetic Resonance Imaging Neutropenia / cerebrospinal fluid, chemically induced*, complications |
Chemical | |
Reg. No./Substance:
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59277-89-3/Acyclovir |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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