| Acyclovir and idoxiuridine treatment of herpes simplex keratitis--a double blind clinical study. | |
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MedLine Citation:
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PMID: 6762044 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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38 patients with herpes simplex keratitis were treated in double blind clinical trial. 18 patients (10 with pure epithelial and 8 with accompanying stromal affection) were treated with 3% acyclovir (ACV) eye ointment, and 20 patients (10 with pure epithelial and 10 with accompanying stromal affection) were treated with 0.5% idoxiuridine (IDU). The cure rate was 94% in the ACV group compared to 70% in the IDU group. This was significantly higher in the ACV group. Only minor adverse reactions were recorded. |
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Authors:
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A Klauber; E Ottovay |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article |
Journal Detail:
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Title: Acta ophthalmologica Volume: 60 ISSN: 0001-639X ISO Abbreviation: Acta Ophthalmol (Copenh) Publication Date: 1982 Oct |
Date Detail:
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Created Date: 1983-04-15 Completed Date: 1983-04-15 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370347 Medline TA: Acta Ophthalmol (Copenh) Country: DENMARK |
Other Details:
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Languages: eng Pagination: 838-44 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acyclovir
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therapeutic use* Clinical Trials as Topic Double-Blind Method Female Humans Idoxuridine / therapeutic use* Keratitis, Dendritic / drug therapy* Male Middle Aged Ointments |
| Chemical | |
Reg. No./Substance:
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0/Ointments; 54-42-2/Idoxuridine; 59277-89-3/Acyclovir |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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