Document Detail

Acyclovir and idoxiuridine treatment of herpes simplex keratitis--a double blind clinical study.
MedLine Citation:
PMID:  6762044     Owner:  NLM     Status:  MEDLINE    
38 patients with herpes simplex keratitis were treated in double blind clinical trial. 18 patients (10 with pure epithelial and 8 with accompanying stromal affection) were treated with 3% acyclovir (ACV) eye ointment, and 20 patients (10 with pure epithelial and 10 with accompanying stromal affection) were treated with 0.5% idoxiuridine (IDU). The cure rate was 94% in the ACV group compared to 70% in the IDU group. This was significantly higher in the ACV group. Only minor adverse reactions were recorded.
A Klauber; E Ottovay
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Acta ophthalmologica     Volume:  60     ISSN:  0001-639X     ISO Abbreviation:  Acta Ophthalmol (Copenh)     Publication Date:  1982 Oct 
Date Detail:
Created Date:  1983-04-15     Completed Date:  1983-04-15     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370347     Medline TA:  Acta Ophthalmol (Copenh)     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  838-44     Citation Subset:  IM    
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MeSH Terms
Acyclovir / therapeutic use*
Clinical Trials as Topic
Double-Blind Method
Idoxuridine / therapeutic use*
Keratitis, Dendritic / drug therapy*
Middle Aged
Reg. No./Substance:
0/Ointments; 54-42-2/Idoxuridine; 59277-89-3/Acyclovir

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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