| Acute zonal occult outer retinopathy: towards a set of diagnostic criteria. | |
| | |
MedLine Citation:
|
PMID: 15615750 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Individuals with acute zonal occult outer retinopathy (AZOOR) present with initially progressive scotomata and photopsia. Characteristically, the extent of the visual field defect is unexplained by fundal examination, but there is marked retinal dysfunction evident electrophysiologically. It is the authors' experience that a group of patients exhibit characteristic clinical and electrophysiological abnormalities, which serve as criteria for a working diagnosis. METHODS: A retrospective observational case series of 28 patients were identified with the clinical diagnosis of AZOOR who shared similar abnormal electrophysiology. Details of the history and ophthalmic findings were obtained from the case notes. RESULTS: Electrophysiology demonstrated a consistent pattern of dysfunction both at the photoreceptor/retinal pigment epithelial complex but also at inner retinal levels, essentially comprising a delayed 30 Hz flicker ERG and a reduction in the EOG light rise. CONCLUSION: This study determines diagnostic criteria applicable to a group of patients with AZOOR, typically those with classic symptomatology. Electrophysiological testing can help avoid lengthy, costly, and potentially invasive investigations, and the unnecessary use of immunosuppressive therapy. |
| | |
Authors:
|
P J Francis; A Marinescu; F W Fitzke; A C Bird; G E Holder |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The British journal of ophthalmology Volume: 89 ISSN: 0007-1161 ISO Abbreviation: Br J Ophthalmol Publication Date: 2005 Jan |
Date Detail:
|
Created Date: 2004-12-23 Completed Date: 2005-01-18 Revised Date: 2009-11-18 |
Medline Journal Info:
|
Nlm Unique ID: 0421041 Medline TA: Br J Ophthalmol Country: England |
Other Details:
|
Languages: eng Pagination: 70-3 Citation Subset: IM |
Affiliation:
|
Department of Electrophysiology, Moorfields Eye Hospital, 162 City Road, London EC1V 2PD, UK. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acute Disease Adult Aged Electrooculography / methods Electroretinography / methods Female Fundus Oculi Humans Male Middle Aged Retinal Diseases / diagnosis*, pathology, physiopathology Retrospective Studies Scotoma / physiopathology Syndrome Vision Disorders / physiopathology |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Surgical induction of chorioretinal venous anastomosis in ischaemic central retinal vein occlusion: ...
Next Document: Subthreshold diode micropulse photocoagulation for the treatment of clinically significant diabetic ...