| Acute vincristine neurotoxicity in the presence of hereditary motor and sensory neuropathy type I. | |
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MedLine Citation:
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PMID: 2685529 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Acute vincristine neurotoxicity leading to a severe motor and sensory neuropathy has been noted in patients with hereditary motor and sensory neuropathy type I (HMSN-I). The case of a 2-year-old boy with acute lymphocytic leukemia and HMSN-I is reported, and additional cases from the literature are reviewed. Severe vincristine neurotoxicity in patients with HMSN-I may be secondary to impairment of both slow and- fast axonal transport. Vincristine should be used with caution in patients with a family history of polyneuropathy. |
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Authors:
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S A McGuire; S M Gospe; G Dahl |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Medical and pediatric oncology Volume: 17 ISSN: 0098-1532 ISO Abbreviation: Med. Pediatr. Oncol. Publication Date: 1989 |
Date Detail:
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Created Date: 1990-01-11 Completed Date: 1990-01-11 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7506654 Medline TA: Med Pediatr Oncol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 520-3 Citation Subset: IM |
Affiliation:
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Department of Neurology, School of Medicine, University of California, Davis 95817. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Charcot-Marie-Tooth Disease
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complications* Child, Preschool Humans Male Muscular Atrophy, Spinal Peripheral Nerves / drug effects* Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy Vincristine / adverse effects* |
| Chemical | |
Reg. No./Substance:
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57-22-7/Vincristine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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