Document Detail

Acute ventricular and aortic thrombosis post chemotherapy.
MedLine Citation:
PMID:  17551165     Owner:  NLM     Status:  MEDLINE    
We present a rare case of spontaneous arterial thrombosis in a 42-year-old male with an acute history of bilateral lower limb pain and weakness. The previous day he had received the first cycle of cisplatin-based chemotherapy for oesophageal adenocarcinoma (T2/3N0/M0). Computed tomography (CT) and angiography showed extensive abdominal aortic thrombus in a native non-aneurysmal or grossly atheromatous aorta with separate thrombus in the left ventricle. We suggest that poor left ventricular function, a hypercoaguable state secondary to malignancy and cisplatin based chemotherapy may have induced severe arterial and intra-cardiac thrombosis.
J F Morlese; T Jeswani; I Beal; P Wylie; J Bell
Related Documents :
1344135 - Antiphospholipid antibodies and ischemic stroke.
8263785 - Comparison of thrombin active site and exosite inhibitors and heparin in experimental m...
17139375 - Focal arterial inflammation is augmented in mice with a deficiency of the protein c gene.
10399665 - Collapse and massive pulmonary edema secondary to thrombosis of a mitral mechanical hea...
3698605 - Equilibrium radionuclide right ventriculography at rest and during exercise in patients...
14634835 - Proximal superficial temporal artery to proximal middle cerebral artery bypass using a ...
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The British journal of radiology     Volume:  80     ISSN:  1748-880X     ISO Abbreviation:  Br J Radiol     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-06-06     Completed Date:  2007-07-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0373125     Medline TA:  Br J Radiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  e75-7     Citation Subset:  AIM; IM    
Royal Free Hospital, Pond Street, London, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Acute Disease
Adenocarcinoma / drug therapy
Antineoplastic Combined Chemotherapy Protocols / adverse effects*
Aortic Diseases / chemically induced*,  radiography
Esophageal Neoplasms / drug therapy
Fatal Outcome
Heart Diseases / chemically induced*,  radiography
Heart Ventricles
Thrombosis / chemically induced*,  radiography
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Detection of an occult thymoma on 99Tcm-Tetrofosmin myocardial scintigraphy.
Next Document:  Lower limb ischaemia caused by fractured osteochondroma of the femur.