Document Detail

Acute transverse myelopathy and cutaneous vasculopathy in primary Sjögren's syndrome.
MedLine Citation:
PMID:  8591805     Owner:  NLM     Status:  MEDLINE    
Neurologic complications of primary Sjögren's syndrome (SS) may be under-estimated. Here, we report a patient with primary SS, who developed acute transverse myelopathy (ATM) and skin purpuric lesions simultaneously. In the first episode of myelopathy, the patient's neurologic deficits improved after steroid therapy. However, she died of recurrent myelopathy with systemic complications 4 months later. Review of the English-language literature revealed only 3 cases of primary SS associated with ATM, none of the 3 patients had skin lesions. Anti-Ro(SS-A) antibodies, and ATM in our patient suggests that immune-mediated vasculopathy may play a role in the pathogenesis of acute myelopathy in primary SS.
R K Lyu; S T Chen; L M Tang; T C Chen
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  European neurology     Volume:  35     ISSN:  0014-3022     ISO Abbreviation:  Eur. Neurol.     Publication Date:  1995  
Date Detail:
Created Date:  1996-04-04     Completed Date:  1996-04-04     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0150760     Medline TA:  Eur Neurol     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  359-62     Citation Subset:  IM    
Department of Neurology, Chang Gung Memorial Hospital, Taipei, Taiwan.
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MeSH Terms
Acute Disease
Fatal Outcome
Myelitis, Transverse / complications*
Purpura / complications*
Sjogren's Syndrome / complications*

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