Document Detail

Acute toxicity of cresols, xylenols, and trimethylphenols to Daphnia magna Straus 1820.
MedLine Citation:
PMID:  3238416     Owner:  NLM     Status:  MEDLINE    
Twenty-four-hour IC50 values (50% immobilization concentration) for phenol, o-cresol, m-cresol, p-cresol, six xylenols, and three trimethylphenols were determined for Daphnia magna under static conditions. Our results show that cresols are more toxic than phenol, that xylenols do not exhibit significantly higher toxicity than cresols, and that trimethylphenols are less toxic than cresols. Thus, no direct relationship can be found between the number and position of methyl groups on the phenol nucleus and their acute toxicity to the water flea.
J Devillers
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Science of the total environment     Volume:  76     ISSN:  0048-9697     ISO Abbreviation:  Sci. Total Environ.     Publication Date:  1988 Sep 
Date Detail:
Created Date:  1989-05-01     Completed Date:  1989-05-01     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0330500     Medline TA:  Sci Total Environ     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  79-83     Citation Subset:  IM    
Institut Pasteur de Lyon, France.
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MeSH Terms
Cresols / toxicity*
Daphnia / drug effects*
Models, Biological
Phenols / toxicity*
Species Specificity
Structure-Activity Relationship
Water Pollutants / toxicity*
Water Pollutants, Chemical / toxicity*
Xylenes / toxicity*
Reg. No./Substance:
0/Cresols; 0/Phenols; 0/Water Pollutants; 0/Water Pollutants, Chemical; 0/Xylenes; 108-68-9/3,5-xylenol; 576-26-1/2,6-xylenol; 95-87-4/2,5-xylenol
Erratum In:
Sci Total Environ 1989 Jan;78:300

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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