| Acute systemic complications in the preterm fetus after asphyxia: role of cardiovascular and blood flow responses. | |
| | |
MedLine Citation:
|
PMID: 16620290 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
1. Poor perfusion of the kidneys and gut, and associated functional impairment, are major problems in the first days of life in very preterm infants. These complications can be associated with a substantial mortality and further problems such as reduced kidney growth and chronic renal problems in later childhood. 2. There is very little information, and consequently considerable debate, about how or even whether to improve perfusion of the vital organs of this most vulnerable group of babies. Current treatments simply do not consistently improve babies' perfusion generally or kidney and gut perfusion and function in particular. 3. In this review we critically examine clinical and experimental evidence that suggests that exposure to low oxygen levels before and during birth may be a significant contributor to impaired systemic perfusion, and highlight areas requiring further research. 4. This knowledge is essential to develop and refine ways of improving perfusion of the kidneys and other vital organs in premature babies. |
| | |
Authors:
|
L Bennet; L Booth; S C Malpas; J S Quaedackers; E Jensen; J Dean; A J Gunn |
Publication Detail:
|
Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
|
Title: Clinical and experimental pharmacology & physiology Volume: 33 ISSN: 0305-1870 ISO Abbreviation: Clin. Exp. Pharmacol. Physiol. Publication Date: 2006 Apr |
Date Detail:
|
Created Date: 2006-04-19 Completed Date: 2006-05-17 Revised Date: 2008-11-21 |
Medline Journal Info:
|
Nlm Unique ID: 0425076 Medline TA: Clin Exp Pharmacol Physiol Country: Australia |
Other Details:
|
Languages: eng Pagination: 291-9 Citation Subset: IM |
Affiliation:
|
Department of Physiology, Faculty of Medicine and Health Sciences, The University of Auckland, Auckland, New Zealand. l.bennet@auckland.ac.nz |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acute Disease Asphyxia Neonatorum / complications*, physiopathology Cardiovascular Physiological Phenomena* Hemodynamics / physiology* Humans Infant, Newborn Infant, Premature / physiology* Regional Blood Flow / physiology |
| Grant Support | |
ID/Acronym/Agency:
|
R01 HD-32752/HD/NICHD NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Skewing of X-chromosome inactivation in three generations of carriers with X-linked chronic granulom...
Next Document: Patient age is a strong independent predictor of 13C-aminopyrine breath test results: a comparative ...