Document Detail


Acute syphilitic interstitial orchitis mimicking testicular malignancy in an HIV-1 infected man diagnosed by Treponema pallidum polymerase chain reaction.
MedLine Citation:
PMID:  19103900     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report a case of acute epididymo-orchitis due to early infectious syphilis, mimicking as testicular malignancy in an undiagnosed HIV-positive individual. He presented with a mass on his testicle and simultaneously had serology consistent with early syphilis. It could not be distinguished from a malignancy, which necessitated urgent orchidectomy. Histology showed endarteritis but no evidence of gummatous involvement. Although treponemes were not detected by staining, the diagnosis was confirmed by the first reported use of Treponema pallidum polymerase chain reaction in a testicular specimen in the UK.
Authors:
R Varma; S Baithun; S Alexander; B T Goh
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  International journal of STD & AIDS     Volume:  20     ISSN:  0956-4624     ISO Abbreviation:  Int J STD AIDS     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2008-12-23     Completed Date:  2009-03-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9007917     Medline TA:  Int J STD AIDS     Country:  England    
Other Details:
Languages:  eng     Pagination:  65-6     Citation Subset:  IM; X    
Affiliation:
Barts and the London NHS Trust, Ambrose King Centre, Royal London Hospital, London E1 1BB. rajesh.varma@bartsandthelondon.nhs.uk
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Adult
Diagnosis, Differential
HIV Infections / complications*
Humans
Male
Orchitis* / diagnosis,  microbiology
Polymerase Chain Reaction / methods*
Syphilis* / diagnosis,  microbiology
Testicular Neoplasms* / diagnosis,  ultrasonography
Testis / microbiology,  ultrasonography
Treponema pallidum / classification,  genetics,  isolation & purification*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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