Document Detail

Acute splenic sequestration crisis in an adolescent with S-C hemoglobinopathy.
MedLine Citation:
PMID:  419029     Owner:  NLM     Status:  MEDLINE    
Acute splenic sequestration crisis occurs rarely as a complication of sickle hemoglobinopathy. It is a medical emergency requiring immediate restoration of intravascular volume with transfusions of fresh packed RBCs. If the blood of the patient under discussion had not contained strong irregular antibodies, the delay in blood transfusion and the subsequent fatal outcome might have been avoided. Whether young children with sickle hemoglobinopathies should be checked periodically for the presence of irregular antibodies is an unanswered question. Monitoring might be important in view of the small but definite risk during childhood of the development of acute splenic sequestration crisis.
K P Rao; R A Seeler
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Postgraduate medicine     Volume:  65     ISSN:  0032-5481     ISO Abbreviation:  Postgrad Med     Publication Date:  1979 Mar 
Date Detail:
Created Date:  1979-04-28     Completed Date:  1979-04-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401147     Medline TA:  Postgrad Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  159-61     Citation Subset:  AIM; IM    
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MeSH Terms
Acute Disease
Anemia, Sickle Cell / complications*
Splenic Diseases / complications*,  pathology,  therapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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