| Acute spermatic cord torsion alters the microcirculation of the contralateral testis. | |
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MedLine Citation:
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PMID: 7490885 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: The purpose of this study was to characterize the hemodynamic changes in the contralateral testis during acute spermatic cord torsion in anesthetized rats. MATERIALS AND METHODS: We used videomicroscopy to examine the microcirculation of the contralateral testis following acute torsion. Specifically, we examined the effect on vasomotion, a rhythmic dilation and constriction of the arterioles that is involved in fluid and nutrient exchange and modulation of local vascular resistance. In a separate set of experiments, blood flow in the contralateral internal spermatic artery was measured with an ultrasonic flow probe during acute torsion. RESULTS: Following 720 degrees torsion, the amplitude of vasomotion in the contralateral testis increased 121% (29.0 +/- 3.9% versus 13.0 +/- 1.7%) compared with controls. Blood flow in the contralateral internal spermatic artery decreased 43% after 2 hours' torsion. CONCLUSIONS: Acute spermatic cord torsion altered the microcirculation by increasing the amplitude of vasomotion and decreased total blood flow to the opposite testis. Because the hydraulic resistance of a blood vessel exhibiting vasomotion is always less than a vessel with the same average but static diameter, the observed microcirculatory changes may be an adaptive response to preserve local flow in the presence of decreased total flow. The long-term consequences of these changes in the microcirculation may affect testicular function and ultimately fertility. |
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Authors:
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P N Kolettis; N T Stowe; S R Inman; A J Thomas |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Journal of urology Volume: 155 ISSN: 0022-5347 ISO Abbreviation: J. Urol. Publication Date: 1996 Jan |
Date Detail:
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Created Date: 1996-01-04 Completed Date: 1996-01-04 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0376374 Medline TA: J Urol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 350-4 Citation Subset: AIM; IM |
Affiliation:
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Department of Urology, Cleveland Clinic Foundation, Ohio 44195, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Animals Arteries / physiology Arterioles / physiology Male Microscopy, Video Rats Rats, Wistar Regional Blood Flow / physiology Spermatic Cord Torsion / physiopathology* Testis / blood supply* Vasoconstriction / physiology Vasodilation / physiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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