Document Detail

Acute silicoproteinosis.
MedLine Citation:
PMID:  190727     Owner:  NLM     Status:  MEDLINE    
A case of alveolar lipoproteinosis associated with silicosis is reported. A 58-year-old man had been exposed to silica for seven years and died three years after the onset of symptoms. Light microscopy of biopsy and necropsy material showed small silicotic nodules, silica particles, and alveolar lipoproteinosis, and ultrastructural studies were performed to define changes in alveolar epithelium and macrophages. The case provides a further example of alveolar lipoproteinosis developing as a response of the lung to injury by an external agent.
J M Xipell; K N Ham; C G Price; D P Thomas
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Thorax     Volume:  32     ISSN:  0040-6376     ISO Abbreviation:  Thorax     Publication Date:  1977 Feb 
Date Detail:
Created Date:  1977-04-30     Completed Date:  1977-04-30     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0417353     Medline TA:  Thorax     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  104-11     Citation Subset:  IM    
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MeSH Terms
Acute Disease
Lipoproteins / metabolism
Middle Aged
Occupational Diseases / chemically induced*,  pathology
Pulmonary Alveolar Proteinosis / chemically induced*,  pathology
Silicon Dioxide / adverse effects*
Silicosis / chemically induced*,  pathology
Reg. No./Substance:
0/Lipoproteins; 7631-86-9/Silicon Dioxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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