| Acute severe memory impairment as a presenting symptom of multiple sclerosis: a clinical case study with 3D double inversion recovery MR imaging. | |
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MedLine Citation:
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PMID: 20846999 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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We present the case of a 21-year-old woman with acute memory impairment. It was initially not recognized as organic in nature. Repeated neuropsychological testing confirmed severely disturbed encoding and recall. Three-dimensional double inversion recovery (3D-DIR) MRI confirmed hippocampal and cortical lesions. Further clinical symptoms, visual evoked potential and MRI suggested a diagnosis of multiple sclerosis (MS). The amnestic syndrome has remained for 5 years. This case illustrates that MS can present with acute cortical symptoms which can be difficult to recognize. The hippocampus can be acutely affected and DIR MRI imaging can help to demonstrate cortical lesions that explain the clinical picture. |
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Authors:
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Jaf Coebergh; Sd Roosendaal; Ch Polman; Jj Geurts; Tcam van Woerkom |
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Publication Detail:
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Type: Journal Article Date: 2010-09-16 |
Journal Detail:
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Title: Multiple sclerosis (Houndmills, Basingstoke, England) Volume: 16 ISSN: 1477-0970 ISO Abbreviation: Mult. Scler. Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-12-01 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9509185 Medline TA: Mult Scler Country: England |
Other Details:
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Languages: eng Pagination: 1521-4 Citation Subset: IM |
Affiliation:
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Department of Neurology and Clinical Neurophysiology, Haga Teaching Hospital, The Hague, The Netherlands. coebergh@doctors.org.uk. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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