Document Detail

Acute severe hemorrhage secondary to arterial invasion in a dog with thyroid carcinoma.
MedLine Citation:
PMID:  12959383     Owner:  NLM     Status:  MEDLINE    
A 7-year-old spayed female Labrador Retriever was referred because of progressive swelling and bruising of the neck, hemothorax, a possible mediastinal mass, and stridor. At the time of admission, the dog was recumbent, mentally dull, tachycardic, and hypothermic. Fluid therapy with hydroxyethyl starch and a balanced electrolyte solution was administered because of presumed hypovolemic shock secondary to hemorrhage; multiple units of packed RBCs and fresh frozen plasma were also administered. On the basis of the computed tomographic images, extensive subcutaneous, subfascial, and cranial mediastinal hemorrhage; hemothorax; prescapular lymphadenopathy; and a contrast-enhancing mass in the left cranioventral aspect of the neck were diagnosed. Exploratory surgery of the neck was performed. All subcutaneous structures were encased in a large blood clot. During dissection of the clot, pulsatile bleeding was observed just caudal to and to the left of the larynx; ligation of the left common carotid artery resulted in immediate cessation of the pulsatile bleeding. Further surgical exploration revealed a 2.5 x 2.5-cm mass adhered to the left common carotid artery at the level of the branching to the left cranial thyroid artery. The mass was removed; the histologic diagnosis was thyroid carcinoma. Three weeks after surgery, treatment with a combination of radiation and chemotherapy (doxorubicin and carboplatin) was begun. Thirteen months after surgery, the dog continued to be free from clinical signs of disease.
Kimberly A Slensky; Susan W Volk; Tobias Schwarz; Lili Duda; Elizabeth A Mauldin; Deborah Silverstein
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of the American Veterinary Medical Association     Volume:  223     ISSN:  0003-1488     ISO Abbreviation:  J. Am. Vet. Med. Assoc.     Publication Date:  2003 Sep 
Date Detail:
Created Date:  2003-09-08     Completed Date:  2003-12-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7503067     Medline TA:  J Am Vet Med Assoc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  649-53, 636     Citation Subset:  IM    
Department of Clinical Studies-Philadelphia, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104-6010, USA.
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MeSH Terms
Blood Transfusion / veterinary
Carcinoma / complications,  pathology,  therapy,  veterinary*
Carotid Artery, Common / pathology,  surgery
Combined Modality Therapy
Dog Diseases / etiology,  pathology*,  therapy
Erythrocyte Transfusion / veterinary
Fluid Therapy / veterinary
Hemorrhage / etiology,  therapy,  veterinary*
Neoplasm Invasiveness
Shock / etiology,  therapy,  veterinary
Thyroid Neoplasms / complications,  pathology,  therapy,  veterinary*
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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