Document Detail

Acute secondary erythermalgia and hypertension in children. Erythermalgia Multidisciplinary Study Group.
MedLine Citation:
PMID:  8582398     Owner:  NLM     Status:  MEDLINE    
We studied the clinical symptoms in nine children (seven females and two males; mean age 11.6 years) with severe but transient acute secondary erythermalgia. The classical symptoms at presentation were episodic attacks of painful burning hands and feet which felt warm with congested appearance of the feet. Each attack lasted for a mean period of 25 days (range from 6 to 56 days). The blood pressure was elevated in seven patients. Intravenous sodium nitroprusside was effective in ameliorating the symptoms with drop in blood pressure to normal in five patients; pizotifene, labetolol, prostaglandin E1 and hypnotherapy were effective in each of four separate cases. The episodes of acute secondary erythermalgia were transient in all and did not recur after a mean follow up period of 1.6 years. These cases suggest that acute secondary erythermalgia, however transient, is not rare and can be associated with mild to moderate hypertension which may respond to sodium nitroprusside. A greater awareness of this condition is necessary to make an accurate and timely diagnosis and institute appropriate therapy in order to prevent undue complications.
J P Drenth; J J Michiels; S Ozsoylu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of pediatrics     Volume:  154     ISSN:  0340-6199     ISO Abbreviation:  Eur. J. Pediatr.     Publication Date:  1995 Nov 
Date Detail:
Created Date:  1996-03-21     Completed Date:  1996-03-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7603873     Medline TA:  Eur J Pediatr     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  882-5     Citation Subset:  IM    
Department of Medicine, University Hospital St Radboud, Nijmegen, The Netherlands.
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MeSH Terms
Acute Disease
Alprostadil / therapeutic use
Child, Preschool
Erythromelalgia / etiology*
Hypertension / complications*,  drug therapy
Labetalol / therapeutic use
Nitroprusside / therapeutic use
Reg. No./Substance:
15078-28-1/Nitroprusside; 36894-69-6/Labetalol; 745-65-3/Alprostadil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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