| Acute reversible myocardial depression associated with sepsis. | |
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MedLine Citation:
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PMID: 12583621 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 30-year-old man was admitted to our hospital for left lobar pneumonia with septic shock. Acute left-sided heart failure became evident as sepsis developed. Echocardiography revealed diffuse severe hypokinesis of the left ventricle (LV) and a pulmonary artery catheter showed Forrester subset II hemodynamics. Along with amelioration of sepsis and decrease of the serum concentrations of tumor necrosis factor-alpha and interleukin-6, LV hypokinesis improved. It is suggested that the patient's heart failure may have been due to functional depression of myocardial contractility resulting from a direct effect of the cytokines towards the cardiomyocytes, the so-called "septic myocardial depression". |
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Authors:
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Makoto Kontani; Yoshiaki Izumiya; Miho Shimizu; Keiichi Yasuma; Akira Inada; Hajime Ohta; Takayuki Ikeda |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Internal medicine (Tokyo, Japan) Volume: 42 ISSN: 0918-2918 ISO Abbreviation: Intern. Med. Publication Date: 2003 Jan |
Date Detail:
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Created Date: 2003-02-13 Completed Date: 2003-06-13 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9204241 Medline TA: Intern Med Country: Japan |
Other Details:
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Languages: eng Pagination: 60-5 Citation Subset: IM |
Affiliation:
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Department of Cardiology, Tsuruga Municipal Hospital, 1-6-60 Mishima-cho, Tsuruga, Fukui 914-8502. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cytokines / blood Echocardiography Heart Failure / etiology*, ultrasonography Humans Inflammation Mediators / blood Male Pneumonia, Pneumococcal / complications Sepsis / complications* Shock, Septic / complications Ventricular Dysfunction, Left / etiology, ultrasonography |
| Chemical | |
Reg. No./Substance:
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0/Cytokines; 0/Inflammation Mediators |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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