| Acute retinal necrosis: Clinical features and therapy options | |
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MedLine Citation:
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PMID: 19820950 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Varicella zoster virus is the most frequent cause of acute retinal necrosis (ARN) followed by herpes simplex virus. Retinal ischemia and optic nerve atrophy are the main causes of the frequently poor final visual outcome in severe cases of ARN. The clinical diagnosis of ARN should be made as early as possible. Acyclovir should be administered intravenously due to its unreliable oral bioavailability. Systemic corticosteroids should be applied to suppress tissue damage caused by the host's inflammatory response. Severe cases of ARN should be treated by early vitrectomy with diagnostic vitreous biopsy, intravitreal aciclovir lavage, intraoperative laser retinopexy and silicone oil tamponade. The role of prophylactic laser retinopexy for prevention of secondary retinal detachment remains to be determined. The cause of different degrees of severity of ARN is unknown. The degree of severity of ARN is probably an independent predictor of the functional outcome. |
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Authors:
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J Hillenkamp; B N?lle; P Rautenberg; H Fickenscher; J Roider |
Publication Detail:
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Type: English Abstract; Journal Article |
Journal Detail:
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Title: Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft Volume: 106 ISSN: 1433-0423 ISO Abbreviation: Ophthalmologe Publication Date: 2009 Dec |
Date Detail:
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Created Date: 2010-01-21 Completed Date: 2010-04-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9206148 Medline TA: Ophthalmologe Country: Germany |
Other Details:
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Languages: ger Pagination: 1058-64 Citation Subset: IM |
Affiliation:
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Klinik f?r Ophthalmologie, Universit?tsklinikum Schleswig-Holstein, Arnold-Heller Str. 3, Haus 25, 24105, Kiel, Deutschland. hillenka@hotmail.com |
Vernacular Title:
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Akute retinale Nekrose : Klinik und Therapieoptionen. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Eye Infections, Viral
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complications,
diagnosis*,
therapy* Humans Retinal Necrosis Syndrome, Acute / diagnosis*, etiology, therapy* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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