Document Detail


Acute respiratory failure that complicates the resuscitation of pediatric patients with scald injuries.
MedLine Citation:
PMID:  10501327     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Respiratory failure that requires endotracheal intubation is an uncommon but potentially fatal complication of scald burns in children. Because scalds are rarely associated with a direct pulmonary injury, the pathophysiology of respiratory failure is unclear. A possible mechanism may be upper airway edema, diminished pulmonary compliance secondary to fluid resuscitation, or both. To identify an at-risk population for intubation after a scald injury, the hospital courses of 174 consecutive patients under the age of 14 years who were admitted after a scald injury to a single burn center during a 6-year period were examined. Seven of these patients (4%) required endotracheal intubation. No patient older than 2.8 years or who had a scald injury that covered less than 19% of the total body surface area required intubation. Patients who required intubation were younger (mean age, 1.4 vs. 2.8 years, P<.001), had a larger mean burn size (29.9% vs. 12.3% total body surface area, P<.001), and required more fluid resuscitation (7.66 vs. 4.07 cc/kg per percentage of total body surface area burned, P<.001) than patients who did not require intubation. Examination of the adequacy of resuscitation revealed that the intubated patients had an average hourly urine output of 0.84 cc/kg during the first 24 hours, suggesting that resuscitation was not excessive. Multivariate analysis demonstrated that both larger burn size (P = .041) and younger age (P = .049) were independent predictors of the need for intubation. Young patients with large body surface area burns that required large volumes of resuscitation comprise an at-risk group for respiratory failure after a scald injury. Increased vigilance is merited during the resuscitation of these patients.
Authors:
A L Zak; D T Harrington; D J Barillo; D F Lawlor; K Z Shirani; C W Goodwin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of burn care & rehabilitation     Volume:  20     ISSN:  0273-8481     ISO Abbreviation:  J Burn Care Rehabil     Publication Date:    1999 Sep-Oct
Date Detail:
Created Date:  1999-10-28     Completed Date:  1999-10-28     Revised Date:  2006-08-15    
Medline Journal Info:
Nlm Unique ID:  8110188     Medline TA:  J Burn Care Rehabil     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  391-9     Citation Subset:  IM    
Affiliation:
US Army Institute of Surgical Research, Fort Sam Houston, Texas 78234, USA.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Body Surface Area
Burns / complications*
Child
Child, Preschool
Female
Fluid Therapy
Humans
Intubation, Intratracheal*
Male
Respiratory Insufficiency / epidemiology,  etiology*,  therapy
Resuscitation
Retrospective Studies
Risk Factors
Comments/Corrections
Comment In:
J Burn Care Rehabil. 2000 May-Jun;21(3):289-90   [PMID:  10850914 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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