Document Detail

Acute renal failure in intensive care burn patients (ARF in burn patients).
MedLine Citation:
PMID:  18182927     Owner:  NLM     Status:  MEDLINE    
The purpose of this study was to establish the incidence and mortality of burn patients with acute renal failure (ARF) at the Helsinki Burn Centre and to analyze the associated factors. The files of 238 intensive care (ICU) patients of a total of 1380 burn patients admitted to our institution between November 1988 and December 2001 were studied retrospectively. Of all admitted burn patients, 17.2% needed ICU. According to our criteria (S-Cr >120 micromol/l = 1.4 mg/dl), 39.1% of the ICU patients suffered from ARF and one in three of these required renal replacement therapy. The proportion of all admitted burn patients requiring renal replacement therapy was 2.3%. The mortality of ICU patients with ARF was 44.1% whereas that of patients without ARF was only 6.9%. Renal function recovered in all survivors. The nonsurvivors had a larger burned total body surface area, were older, and had more inhalation injuries and a higher abbreviated burn severity index score. The prognosis for patients with early ARF was worse than that for patients with late ARF. Rhabdomyolysis caused by flame injury was associated with high mortality. In this study we observed that ARF is associated with higher mortality even in minor burns when compared with patients without ARF. Flame burn with rhabdomyolysis and subsequent ARF predicts very poor survival. If a patient with severe ARF survives, the renal failure recovers over time.
Kukka-Maaria Mustonen; Jyrki Vuola
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of burn care & research : official publication of the American Burn Association     Volume:  29     ISSN:  1559-047X     ISO Abbreviation:  -     Publication Date:    2008 Jan-Feb
Date Detail:
Created Date:  2008-01-09     Completed Date:  2008-03-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101262774     Medline TA:  J Burn Care Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  227-37     Citation Subset:  IM    
Helsinki Burn Centre, Department of Plastic Surgery, Helsinki University Hospital, Finland.
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MeSH Terms
Acute Disease
Burns / complications*,  mortality,  physiopathology
Health Status Indicators
Intensive Care Units / statistics & numerical data*
Kidney Failure, Acute / epidemiology,  etiology*,  mortality
Length of Stay
Middle Aged
Retrospective Studies
Risk Factors
Severity of Illness Index
Sickness Impact Profile

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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