Document Detail


Acute recurrent polyhydramnios: a combination of amniocenteses and NSAID may be curative rather than palliative.
MedLine Citation:
PMID:  17228156     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Acute recurrent polyhydramnios is a rare occurrence characterized by a poor fetal outcome. This is a case report describing a 34-year-old woman presenting with acute recurrent polyhydramnios. Treatment with non-steroidal anti-inflammatory drugs (NSAID) and therapeutic amniocenteses was initiated immediately and resulted in a decreased amniotic fluid production from 30 weeks' gestation. Even after the discontinuation of NSAID treatment, the amniotic fluid production normalized, and the woman delivered a healthy boy at 39 weeks 2 days' gestation. Amniotic prolactin was measured at three occasions using an enzyme-linked immunosorbent assay. As in normal pregnancies, amniotic prolactin levels decreased by 80% from highest to lowest value in this case of resolving acute recurrent polyhydramnios.
Authors:
Line Rode; Anne Bundgaard; Lillian Skibsted; Lars Odum; Connie Jørgensen; Jens Langhoff-Roos
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2007-01-16
Journal Detail:
Title:  Fetal diagnosis and therapy     Volume:  22     ISSN:  1015-3837     ISO Abbreviation:  Fetal. Diagn. Ther.     Publication Date:  2007  
Date Detail:
Created Date:  2007-04-13     Completed Date:  2007-05-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9107463     Medline TA:  Fetal Diagn Ther     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  186-9     Citation Subset:  IM    
Copyright Information:
(c) 2007 S. Karger AG, Basel.
Affiliation:
Department of Obstetrics and Gynecology, Copenhagen University Hospital, Copenhagen, Denmark. linerode@dadlnet.dk
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Adult
Amniocentesis / methods*
Amniotic Fluid / metabolism
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
Combined Modality Therapy
Female
Humans
Infant, Newborn
Male
Polyhydramnios / drug therapy*,  etiology,  metabolism,  therapy*
Pregnancy
Prolactin / metabolism
Receptors, Prolactin / metabolism
Recurrence
Chemical
Reg. No./Substance:
0/Anti-Inflammatory Agents, Non-Steroidal; 0/Receptors, Prolactin; 9002-62-4/Prolactin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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